Protein: TROP
Trophinin (MAGE-D3 antigen)

Gene: TROP, TRO
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q12816

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007566 - embryo implantation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

643808

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

2

High-throughput

0.667

High

679331

DNJB2
DnaJ homolog subfamily B member 2

3

2

High-throughput

0.667

High

946096

MLF1
Myeloid leukemia factor 1

3

2

High-throughput

0.667

High

989728

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

3

2

High-throughput

0.656

High

1028970

TIAR
Nucleolysin TIAR

2

3

High-throughput

0.628

High

1086548

PPM1E
Protein phosphatase 1E

2

3

High-throughput

0.628

High

1086532

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

5

Small-scale

0.624

High

1086562

MAGD2
Melanoma-associated antigen D2

1

17

High-throughput

0.618

High

888452

TSP3
Thrombospondin-3

3

2

High-throughput

0.609

High

1086552

FAF2
FAS-associated factor 2

3

4

High-throughput

0.609

High

192713

ARPC5
Actin-related protein 2/3 complex subunit 5

2

0

High-throughput

0.602

High

1086540

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.602

High

1086557

NXF2
Nuclear RNA export factor 2

2

0

High-throughput

0.602

High

630261

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

9

High-throughput

0.536

High

897156

TUB
Tubby protein homolog

1

1

High-throughput

0.536

High

1086534

DYLT4
Dynein light chain Tctex-type 4

1

1

High-throughput

0.536

High

1086544

H2BWT
Histone H2B type W-T

1

9

High-throughput

0.536

High

1086556

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

1086563

SRPK3
SRSF protein kinase 3

1

7

High-throughput

0.536

High

1051913

KPCD
Protein kinase C delta type

1

3

Small-scale

0.515

High

1060862

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

0

High-throughput

0.513

High

1086528

IRF3
Interferon regulatory factor 3

1

0

High-throughput

0.513

High

1086553

TMM74
Transmembrane protein 74

1

0

High-throughput

0.513

High

1086550

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

16

High-throughput

0.508

High

391236

FRIL
Ferritin light chain

1

2

High-throughput

0.489

High

859803

RL28
Large ribosomal subunit protein eL28

1

3

High-throughput

0.489

High

1086546

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.489

High

1086549

LAR4B
La-related protein 4B

1

3

High-throughput

0.489

High

1086561

KLK12
Kallikrein-12

1

3

High-throughput

0.489

High

1086526

FHL3
Four and a half LIM domains protein 3

1

5

High-throughput

0.481

High

241526

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

256846

H2B1K
Histone H2B type 1-K

1

8

High-throughput

0.479

High

507886

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.479

High

586660

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

615762

RL17
Large ribosomal subunit protein uL22

1

3

High-throughput

0.479

High

686121

RL13
Large ribosomal subunit protein eL13

1

3

High-throughput

0.479

High

761989

GRK5
G protein-coupled receptor kinase 5

1

7

High-throughput

0.479

High

838450

GRIA1
Glutamate receptor 1

1

3

High-throughput

0.479

High

838489

GRIA2
Glutamate receptor 2

1

3

High-throughput

0.479

High

838526

GRIA3
Glutamate receptor 3

1

3

High-throughput

0.479

High

846741

GRK6
G protein-coupled receptor kinase 6

1

8

High-throughput

0.479

High

868504

RL29
Large ribosomal subunit protein eL29

1

1

High-throughput

0.479

High

870105

GRIA4
Glutamate receptor 4

1

3

High-throughput

0.479

High

980727

H2B1C
Histone H2B type 1-C/E/F/G/I

1

8

High-throughput

0.479

High

1086533

MK06
Mitogen-activated protein kinase 6

1

4

High-throughput

0.479

High

1086535

PCID2
PCI domain-containing protein 2

1

2

High-throughput

0.479

High

1086536

H2B2F
Histone H2B type 2-F

1

8

High-throughput

0.479

High

1086551

H2B1H
Histone H2B type 1-H

1

8

High-throughput

0.479

High

684985

DNMT1
DNA

1

0

High-throughput

0.458

High

1045224

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1086529

RFTN1
Raftlin

1

0

High-throughput

0.458

High

1086541

LIN54
Protein lin-54 homolog

1

0

High-throughput

0.458

High

1086543

H32
Histone H3.2

1

0

High-throughput

0.458

High

1086554

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

0

High-throughput

0.458

High

337645

GNAS3
Neuroendocrine secretory protein 55

1

1

High-throughput

0.445

High

1086537

RBG1L
Rab GTPase-activating protein 1-like

1

2

High-throughput

0.445

High

1086542

NBEL2
Neurobeachin-like protein 2

1

9

High-throughput

0.445

High

1015977

RL19
Large ribosomal subunit protein eL19

1

2

High-throughput

0.437

High

1086525

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

1

High-throughput

0.437

High

1086531

PCM1
Pericentriolar material 1 protein

1

2

High-throughput

0.437

High

1086538

ARMC3
Armadillo repeat-containing protein 3

1

4

High-throughput

0.437

High

1086547

DCAF4
DDB1- and CUL4-associated factor 4

1

2

High-throughput

0.437

High

1086555

LLPH
Protein LLP homolog

1

1

High-throughput

0.437

High

1086558

RC3H2
Roquin-2

1

8

High-throughput

0.437

High

1086560

CCD39
Coiled-coil domain-containing protein 39

1

10

High-throughput

0.437

High

1086539

A16L1
Autophagy-related protein 16-1

1

11

High-throughput

0.407

High

1086559

SACA1
Sperm acrosome membrane-associated protein 1

3

0

High-throughput

0.347

High

85255

RBG10
Rab GTPase-activating protein 1-like, isoform 10

2

0

High-throughput

0.318

High

1086527

BYST
Bystin

1

0

Small-scale

0.286

High

1086489

TROAP
Tastin

1

0

Small-scale

0.269

Low

1086530

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

0

High-throughput

0.269

Low

547308

CP2A6
Cytochrome P450 2A6

1

0

High-throughput

0.249

Low

1086545

BBOF1
Basal body-orientation factor 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025