Interactor 1: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 25900982, 28514442, 10644755, 31406304, 33961781, 19615732, 29150431, 37689310
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Beta-TrCP_D~Beta-TrCP_D, F-box-like~F-box-like, WD40~WD40
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005829 - cytosol
GO:0006470 - protein dephosphorylation
GO:0016055 - Wnt signaling pathway
GO:0016567 - protein ubiquitination
and 11 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 542
Hs

1 605
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+ Ce
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Last updated: 15 Jul 2024