Protein: ZC3HF
Zinc finger CCCH domain-containing protein 15 (DRG family-regulatory protein 1) (Likely ortholog of mouse immediate early response erythropoietin 4)

Gene: ZC3HF, ZC3H15
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q8WU90

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1356380

DRG1
Developmentally-regulated GTP-binding protein 1

11

3

Small-scale

0.980

High

992879

RACK1
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.691

High

1356352

PSPC1
Paraspeckle component 1

1

1

High-throughput

0.691

High

1356364

RBM42
RNA-binding protein 42

1

1

High-throughput

0.691

High

1356379

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.691

High

242394

PRKN
E3 ubiquitin-protein ligase parkin

3

1

High-throughput

0.640

High

1356363

DNJC2
DnaJ homolog subfamily C member 2

2

2

High-throughput

0.621

High

472919

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

2

High-throughput

0.618

High

620490

NUCL
Nucleolin

1

1

High-throughput

0.618

High

346107

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

3

0

High-throughput

0.613

High

342270

BRD1
Bromodomain-containing protein 1

2

1

Small-scale

0.611

High

585810

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

2

0

High-throughput

0.602

High

1356381

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.586

High

396588

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

303602

SRP72
Signal recognition particle subunit SRP72

1

1

High-throughput

0.536

High

969996

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

997887

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.527

High

414288

P53
Cellular tumor antigen p53

1

0

High-throughput

0.513

High

447253

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

479450

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

821477

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.513

High

1152168

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1328242

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.513

High

1356370

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.513

High

1356376

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

568575

TNNT1
Troponin T, slow skeletal muscle

1

0

High-throughput

0.486

High

185881

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

173130

XPO1
Exportin-1

1

2

High-throughput

0.479

High

247394

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.479

High

315805

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

425581

ISG15
Ubiquitin-like protein ISG15

1

1

High-throughput

0.479

High

445987

ENOA
Alpha-enolase

1

2

High-throughput

0.479

High

606936

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

680441

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

831119

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

832928

CETN2
Centrin-2

1

1

High-throughput

0.479

High

954204

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

982496

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

982751

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.479

High

1092187

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

1254798

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1356354

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1356355

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1356369

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.479

High

1356371

TRI36
E3 ubiquitin-protein ligase TRIM36

1

1

High-throughput

0.479

High

1356377

XPO7
Exportin-7

1

2

High-throughput

0.479

High

1356378

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

136945

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.458

High

319932

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

325003

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

372672

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

412316

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

424437

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.458

High

556243

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

582896

EZRI
Ezrin

1

0

High-throughput

0.458

High

643951

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

791570

SYUA
Alpha-synuclein

1

0

Small-scale

0.458

High

867294

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

904962

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

941219

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

951778

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

961069

MGN
Protein mago nashi homolog

1

0

High-throughput

0.458

High

965109

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

970831

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1045565

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1090818

TRAF2
TNF receptor-associated factor 2

1

0

Small-scale

0.458

High

1107051

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1107963

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1113823

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1122529

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

1123733

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.458

High

1133289

MTF1
Metal regulatory transcription factor 1

1

0

High-throughput

0.458

High

1138429

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1161568

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1276534

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1289483

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1313287

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1356360

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

1356361

FMNL2
Formin-like protein 2

1

0

High-throughput

0.458

High

1356362

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.458

High

1356365

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1356366

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1356372

ANLN
Anillin

1

0

High-throughput

0.458

High

1356373

C2D2A
Coiled-coil and C2 domain-containing protein 2A

1

0

High-throughput

0.458

High

1356374

CTNL1
Alpha-catulin

1

0

High-throughput

0.458

High

1356375

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

430162

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

934907

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.445

High

1356359

DNJC1
DnaJ homolog subfamily C member 1

1

2

High-throughput

0.437

High

401198

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.426

High

530122

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

942775

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

1209433

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1356356

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

887047

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

1356353

TM9S4
Transmembrane 9 superfamily member 4

1

0

High-throughput

0.279

Low

1356368

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.265

Low

377668

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

642989

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.249

Low

1356357

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1356367

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1292268

S2611
Sodium-independent sulfate anion transporter

1

0

High-throughput

0.232

Low

1356358

S45A3
Solute carrier family 45 member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025