Interactor 1: PACN3 (Q9UKS6)
Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511)
Gene: PACSIN3

Interactor 2: PACN2 (Q9UNF0)
Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII)
Gene: PACSIN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 32296183, 11082044, 33961781, 35271311, 26186194, 28514442, unassigned1304
Identification Methods two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FCH~FCH, FCH~SH3_9, SH3_9~SH3_9
Common GO terms GO:0005543 - phospholipid binding
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 6 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 424
Hs

1 486
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+ Dm

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Last updated: 15 Jul 2024