Protein: CCD12
Coiled-coil domain-containing protein 12

Gene: CCD12, CCDC12
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q8WUD4

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005684 - U2-type spliceosomal complex
GO:0071014 - post-mRNA release spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1128068

DHX8
ATP-dependent RNA helicase DHX8

5

1

High-throughput

0.712

High

1356558

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

4

2

High-throughput

0.694

High

1356581

PRP19
Pre-mRNA-processing factor 19

3

1

High-throughput

0.675

High

1286208

RALYL
RNA-binding Raly-like protein

3

2

High-throughput

0.667

High

1356567

YJU2
Splicing factor YJU2

3

1

High-throughput

0.667

High

1346861

SNIP1
Smad nuclear-interacting protein 1

4

0

High-throughput

0.664

High

1356568

CRNL1
Crooked neck-like protein 1

2

3

High-throughput

0.644

High

485694

RU2A
U2 small nuclear ribonucleoprotein A'

3

0

High-throughput

0.638

High

1356562

USB1
U6 snRNA phosphodiesterase 1

3

0

High-throughput

0.638

High

1356582

PPIE
Peptidyl-prolyl cis-trans isomerase E

3

0

High-throughput

0.638

High

351342

SYF2
Pre-mRNA-splicing factor SYF2

3

0

High-throughput

0.634

High

973774

RUXE
Small nuclear ribonucleoprotein E

3

0

High-throughput

0.634

High

991215

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

1

High-throughput

0.628

High

974167

RUXG
Small nuclear ribonucleoprotein G

2

4

High-throughput

0.611

High

1356560

LRC46
Leucine-rich repeat-containing protein 46

3

1

High-throughput

0.609

High

1356566

WDR83
WD repeat domain-containing protein 83

3

2

High-throughput

0.609

High

462532

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

2

4

High-throughput

0.601

High

1356561

CDC5L
Cell division cycle 5-like protein

2

0

High-throughput

0.585

High

298036

SPF27
Pre-mRNA-splicing factor SPF27

2

0

High-throughput

0.576

High

1138430

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

0

High-throughput

0.576

High

848809

MAGAA
Melanoma-associated antigen 10

2

1

High-throughput

0.571

High

251021

PRP17
Pre-mRNA-processing factor 17

1

3

High-throughput

0.536

High

471890

RU2B
U2 small nuclear ribonucleoprotein B''

1

2

High-throughput

0.536

High

478127

SNRPA
U1 small nuclear ribonucleoprotein A

1

3

High-throughput

0.536

High

574388

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

1

High-throughput

0.536

High

833548

BUD31
Protein BUD31 homolog

1

1

High-throughput

0.536

High

1016537

SRSF3
Serine/arginine-rich splicing factor 3

1

2

High-throughput

0.536

High

1099455

SRSF6
Serine/arginine-rich splicing factor 6

1

1

High-throughput

0.536

High

1127032

RBM39
RNA-binding protein 39

1

1

High-throughput

0.536

High

1160013

SRSF7
Serine/arginine-rich splicing factor 7

1

2

High-throughput

0.536

High

1180470

C19L2
CWF19-like protein 2

1

1

High-throughput

0.536

High

1229498

C19L1
CWF19-like protein 1

1

1

High-throughput

0.536

High

1356570

DHX35
Probable ATP-dependent RNA helicase DHX35

1

1

High-throughput

0.536

High

1356572

SYF1
Pre-mRNA-splicing factor SYF1

1

3

High-throughput

0.536

High

1356580

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

1

High-throughput

0.536

High

245129

AQR
RNA helicase aquarius

1

0

High-throughput

0.513

High

272973

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.513

High

286006

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.513

High

317658

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.513

High

335883

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.513

High

480238

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

542129

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

973992

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

1111136

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1149141

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1160219

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

1168848

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

0

High-throughput

0.513

High

1356565

GPTC1
G patch domain-containing protein 1

1

0

High-throughput

0.513

High

1356575

RBM22
Pre-mRNA-splicing factor RBM22

1

0

High-throughput

0.513

High

1356578

CWC15
Spliceosome-associated protein CWC15 homolog

1

0

High-throughput

0.513

High

1356588

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

0

High-throughput

0.513

High

1356590

NUB1
NEDD8 ultimate buster 1

1

0

High-throughput

0.513

High

256650

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

2

High-throughput

0.489

High

848688

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.489

High

1356554

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

1

High-throughput

0.489

High

372675

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406428

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

129278

MEN1
Menin

1

0

High-throughput

0.458

High

134811

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.458

High

260208

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

589251

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

854894

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.458

High

879300

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

980041

H4
Histone H4

1

0

High-throughput

0.458

High

1155581

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1156792

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1352651

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1356579

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1356585

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.458

High

569262

YJU2B
Probable splicing factor YJU2B

1

1

High-throughput

0.445

High

1227142

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.437

High

1356587

LC7L2
Putative RNA-binding protein Luc7-like 2

1

1

High-throughput

0.437

High

71596

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

4

High-throughput

0.407

High

887048

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1356569

ATG5
Autophagy protein 5

4

0

High-throughput

0.359

High

1356591

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

3

0

High-throughput

0.347

High

1090265

ELAV2
ELAV-like protein 2

2

0

High-throughput

0.328

High

1356555

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

0

High-throughput

0.328

High

1356556

K1143
Uncharacterized protein KIAA1143

2

0

High-throughput

0.328

High

1356564

LZTS2
Leucine zipper putative tumor suppressor 2

2

0

High-throughput

0.328

High

1309667

ARHGJ
Rho guanine nucleotide exchange factor 19

2

0

High-throughput

0.298

High

608314

EGLN
Endoglin

1

0

High-throughput

0.279

Low

666008

IBP5
Insulin-like growth factor-binding protein 5

1

0

High-throughput

0.279

Low

692761

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

706236

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

718436

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.279

Low

1348923

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

1356557

LDAF1
Lipid droplet assembly factor 1

1

0

High-throughput

0.279

Low

1356559

PABP5
Polyadenylate-binding protein 5

1

0

High-throughput

0.279

Low

1356573

CT141
Uncharacterized protein C20orf141

1

0

High-throughput

0.279

Low

1356574

DJC17
DnaJ homolog subfamily C member 17

1

0

High-throughput

0.279

Low

1356576

TMM51
Transmembrane protein 51

1

0

High-throughput

0.279

Low

1356586

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.279

Low

1356589

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.279

Low

1356563

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.251

Low

358756

LDHA
L-lactate dehydrogenase A chain

1

0

High-throughput

0.249

Low

939394

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.249

Low

1290612

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

1356571

RC3H2
Roquin-2

1

0

High-throughput

0.249

Low

1356577

PLK2
Serine/threonine-protein kinase PLK2

1

0

High-throughput

0.249

Low

1356584

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

0

High-throughput

0.249

Low

1356583

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025