HitPredict

Interactor 1: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Interactor 2: STRAP (Q9Y3F4)
Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD)
Gene: STRAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35915203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2610 Hs			1 350
+	Hs
		1346968 HECD1_HUMAN (1-2610): 0: 2419: 100.00		NLE1_HUMAN (126-349): 2.92e-48: 170: 16.42
+	Hs
		1288384 HECD1_HUMAN (1-2610): 0: 2419: 100.00		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		1281471 HECD1_HUMAN (1-2610): 0: 2419: 100.00		FBXW7_HUMAN (209-344): 2.04e-24: 106: 15.94
+	Hs
		903601 HECD1_HUMAN (1-2610): 0: 2419: 100.00		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		197105 HECD1_HUMAN (1-2610): 0: 2419: 100.00		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47
+	Hs
		1032173 HECD1_HUMAN (1-2610): 0: 2419: 100.00		EIF3I_HUMAN (13-127): 7.75e-09: 58.4: 20.77
+	Hs
		125811 WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86		STRAP_HUMAN (1-350): 2.21e-84: 261: 100.00
+	Hs
		304289 UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		304102 UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		1032165 HECW2_HUMAN (1360-2609): 2.26e-127: 444: 14.40		EIF3I_HUMAN (13-127): 7.75e-09: 58.4: 20.77
+	Hs
		304188 UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94		SMU1_HUMAN (26-293): 7.19e-16: 80.5: 26.87
+	Sc
		765276 RSP5_YEAST (2265-2608): 2.06e-105: 360: 20.86		EIF3I_YEAST (11-291): 1.3e-23: 101: 27.85
+	Hs
		125310 WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		125431 WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86		EIF3I_HUMAN (13-127): 7.75e-09: 58.4: 20.77
+	Ce
		1281030 Q9GUP2_CAEEL (2359-2608): 2.04e-79: 297: 29.57		EIF3I_CAEEL (98-308): 2.81e-19: 88.9: 17.18
+	Hs
		1056609 TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03		FBXW7_HUMAN (209-344): 2.04e-24: 106: 15.94
+	Hs
		1032091 TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03		EIF3I_HUMAN (13-127): 7.75e-09: 58.4: 20.77
+	Hs
		903156 UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09