HitPredict

Interactor 1: PADI3 (Q9ULW8)
Protein-arginine deiminase type-3 (EC 3.5.3.15) (Peptidylarginine deiminase III) (Protein-arginine deiminase type III)
Gene: PADI3

Interactor 2: PADI4 (Q9UM07)
Protein-arginine deiminase type-4 (EC 3.5.3.15) (HL-60 PAD) (Peptidylarginine deiminase IV) (Protein-arginine deiminase type IV)
Gene: PADI4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PAD~PAD, PAD~PAD_M, PAD~PAD_N, PAD_M~PAD_M, PAD_M~PAD_N, PAD_N~PAD_N
Common GO terms	GO:0004668 - protein-arginine deiminase activity GO:0005509 - calcium ion binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 1 others more... GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 663
+	Hs
		1356817 PADI3_HUMAN (1-664): 0: 1177: 100.00		PADI1_HUMAN (1-663): 0: 1141: 56.95
+	Hs
		1357109 PADI3_HUMAN (1-664): 0: 1177: 100.00		PADI3_HUMAN (1-663): 0: 1129: 55.61
+	Hs
		1357176 PADI4_HUMAN (1-664): 0: 1105: 55.90		PADI4_HUMAN (1-663): 0: 1145: 100.00