Protein: PDIP3
Polymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46) (S6K1 Aly/REF-like target) (SKAR)

Gene: PDIP3, POLDIP3
Organism: Homo sapiens
Interactions: 221
UniProt ID: Q9BY77

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

658622

KS6B1
Ribosomal protein S6 kinase beta-1

2

4

Small-scale

0.815

High

1066769

NCBP1
Nuclear cap-binding protein subunit 1

2

1

Small-scale

0.802

High

1417827

ZRAN1
Ubiquitin thioesterase ZRANB1

2

3

High-throughput

0.757

High

485382

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

1

High-throughput

0.754

High

1194354

LARP7
La-related protein 7

2

4

High-throughput

0.754

High

1148389

KS6A1
Ribosomal protein S6 kinase alpha-1

1

6

Small-scale

0.692

High

244278

NUAK1
NUAK family SNF1-like kinase 1

1

2

High-throughput

0.691

High

478194

SNRPA
U1 small nuclear ribonucleoprotein A

1

3

High-throughput

0.691

High

692127

MARK3
MAP/microtubule affinity-regulating kinase 3

1

1

High-throughput

0.691

High

889806

CLK3
Dual specificity protein kinase CLK3

1

3

High-throughput

0.691

High

1109208

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

4

High-throughput

0.691

High

1115983

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

5

High-throughput

0.691

High

1290134

THOC4
THO complex subunit 4

1

8

High-throughput

0.691

High

1417838

KLH20
Kelch-like protein 20

3

1

High-throughput

0.667

High

807566

IF4A3
Eukaryotic initiation factor 4A-III

3

5

Small-scale

0.657

High

1006679

SRPK2
SRSF protein kinase 2

1

5

High-throughput

0.647

High

373065

MYC
Myc proto-oncogene protein

3

3

High-throughput

0.640

High

157811

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.618

High

194330

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.618

High

401432

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.618

High

685715

U2AF2
Splicing factor U2AF 65 kDa subunit

1

8

High-throughput

0.618

High

911671

NCBP2
Nuclear cap-binding protein subunit 2

1

5

High-throughput

0.618

High

986690

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.618

High

1088543

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

2

High-throughput

0.618

High

1127137

RBM39
RNA-binding protein 39

1

2

High-throughput

0.618

High

1132950

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

2

High-throughput

0.618

High

1152617

ELAV1
ELAV-like protein 1

1

3

High-throughput

0.618

High

1197557

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

2

High-throughput

0.618

High

1417816

RC3H2
Roquin-2

1

2

High-throughput

0.618

High

1417825

KS6B2
Ribosomal protein S6 kinase beta-2

1

4

High-throughput

0.618

High

1311098

UBR1
E3 ubiquitin-protein ligase UBR1

2

0

High-throughput

0.602

High

1372069

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.589

High

1015298

ERH
Enhancer of rudimentary homolog

2

1

Small-scale

0.586

High

352541

TOP3B
DNA topoisomerase 3-beta-1

2

0

High-throughput

0.585

High

980271

H4
Histone H4

2

1

High-throughput

0.584

High

1135088

CUL7
Cullin-7

2

1

High-throughput

0.584

High

1205974

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

4

High-throughput

0.584

High

1384016

EXOS8
Exosome complex component RRP43

2

1

High-throughput

0.584

High

1411279

LZTS2
Leucine zipper putative tumor suppressor 2

2

5

High-throughput

0.584

High

1209618

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.575

High

218729

TGON2
Trans-Golgi network integral membrane protein 2

2

1

High-throughput

0.571

High

582943

EZRI
Ezrin

2

1

High-throughput

0.571

High

1198654

NCBP3
Nuclear cap-binding protein subunit 3

2

3

High-throughput

0.571

High

503708

SBK3
Uncharacterized serine/threonine-protein kinase SBK3

1

2

High-throughput

0.555

High

257068

F262
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

1

1

High-throughput

0.536

High

471227

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.536

High

481376

HMGB1
High mobility group protein B1

1

4

High-throughput

0.536

High

574459

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

2

High-throughput

0.536

High

908457

HDGF
Hepatoma-derived growth factor

1

3

High-throughput

0.536

High

1117216

THOC5
THO complex subunit 5

1

2

High-throughput

0.536

High

1118151

DX39B
Spliceosome RNA helicase DDX39B

1

10

High-throughput

0.536

High

1199682

KLH22
Kelch-like protein 22

1

1

High-throughput

0.536

High

1341018

THOC2
THO complex subunit 2

1

6

High-throughput

0.536

High

1368797

EZH1
Histone-lysine N-methyltransferase EZH1

1

4

High-throughput

0.536

High

1389762

RBM33
RNA-binding protein 33

1

1

High-throughput

0.536

High

1390966

THOC1
THO complex subunit 1

1

2

High-throughput

0.536

High

1402173

PRPK
EKC/KEOPS complex subunit TP53RK

1

2

High-throughput

0.536

High

1417817

E41L5
Band 4.1-like protein 5

1

1

High-throughput

0.536

High

1417822

BCLF1
Bcl-2-associated transcription factor 1

1

6

High-throughput

0.536

High

1417837

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

1

High-throughput

0.536

High

1417832

HECD1
E3 ubiquitin-protein ligase HECTD1

2

3

High-throughput

0.533

High

1063595

GOGA2
Golgin subfamily A member 2

2

5

High-throughput

0.526

High

1372294

H2B1H
Histone H2B type 1-H

1

1

High-throughput

0.515

High

273451

KDM4A
Lysine-specific demethylase 4A

1

0

High-throughput

0.513

High

292931

RNH2A
Ribonuclease H2 subunit A

1

0

High-throughput

0.513

High

407706

S100B
Protein S100-B

1

0

High-throughput

0.513

High

584043

FOSL1
Fos-related antigen 1

1

0

High-throughput

0.513

High

960546

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.513

High

1013172

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.513

High

1403313

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

1

0

High-throughput

0.513

High

1417810

TOLIP
Toll-interacting protein

1

0

High-throughput

0.513

High

1417812

SENP3
Sentrin-specific protease 3

1

0

High-throughput

0.513

High

1417833

TPX2
Targeting protein for Xklp2

1

0

High-throughput

0.513

High

1417839

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.513

High

1417842

MB212
Protein mab-21-like 2

1

0

High-throughput

0.513

High

225101

TLX3
T-cell leukemia homeobox protein 3

1

3

High-throughput

0.500

High

226594

TLX2
T-cell leukemia homeobox protein 2

1

2

High-throughput

0.500

High

456154

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

1

High-throughput

0.500

High

641251

FGFR2
Fibroblast growth factor receptor 2

1

6

High-throughput

0.500

High

710887

EPHB2
Ephrin type-B receptor 2

1

4

High-throughput

0.500

High

776124

SOX5
Transcription factor SOX-5

1

6

High-throughput

0.500

High

776243

SOX6
Transcription factor SOX-6

1

7

High-throughput

0.500

High

872709

SOX2
Transcription factor SOX-2

1

6

High-throughput

0.500

High

932128

EPHA4
Ephrin type-A receptor 4

1

4

High-throughput

0.500

High

595582

H15
Histone H1.5

1

0

High-throughput

0.493

High

1410936

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

4

High-throughput

0.489

High

180383

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.481

High

269366

HSF2B
Heat shock factor 2-binding protein

1

1

High-throughput

0.481

High

292392

RA51D
DNA repair protein RAD51 homolog 4

1

1

High-throughput

0.481

High

332580

CCDB1
Cyclin-D1-binding protein 1

1

1

High-throughput

0.481

High

733270

OTX2
Homeobox protein OTX2

1

2

High-throughput

0.481

High

974039

RUXF
Small nuclear ribonucleoprotein F

1

3

High-throughput

0.481

High

1146145

K1H1
Keratin, type I cuticular Ha1

1

3

High-throughput

0.481

High

1230241

K1C40
Keratin, type I cytoskeletal 40

1

3

High-throughput

0.481

High

1238113

HMBX1
Homeobox-containing protein 1

1

3

High-throughput

0.481

High

1332032

BANP
Protein BANP

1

1

High-throughput

0.481

High

1336460

PNMA1
Paraneoplastic antigen Ma1

1

2

High-throughput

0.481

High

1350440

BICD2
Protein bicaudal D homolog 2

1

5

High-throughput

0.481

High

1358992

TEKT4
Tektin-4

1

2

High-throughput

0.481

High

1361150

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

1381638

GTPB3
5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial

1

5

High-throughput

0.481

High

1417829

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

4

High-throughput

0.481

High

185989

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

1118770

KLF5
Krueppel-like factor 5

1

0

High-throughput

0.479

High

67572

MYH7B
Myosin-7B

1

1

High-throughput

0.479

High

223304

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

248075

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

260409

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

272443

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.479

High

277810

H2AY
Core histone macro-H2A.1

1

2

High-throughput

0.479

High

283138

PSIP1
PC4 and SFRS1-interacting protein

1

4

High-throughput

0.479

High

315979

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.479

High

320034

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

325095

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

326018

UBR5
E3 ubiquitin-protein ligase UBR5

1

1

Small-scale

0.479

High

406600

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

414554

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

419187

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.479

High

537843

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

558384

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

589605

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

607076

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

674315

BRD2
Bromodomain-containing protein 2

1

7

High-throughput

0.479

High

696418

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

765010

CTNB1
Catenin beta-1

1

2

High-throughput

0.479

High

769088

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

837085

ELK3
ETS domain-containing protein Elk-3

1

1

High-throughput

0.479

High

846934

ETV4
ETS translocation variant 4

1

1

High-throughput

0.479

High

851662

GATA4
Transcription factor GATA-4

1

1

High-throughput

0.479

High

851809

NKX21
Homeobox protein Nkx-2.1

1

6

High-throughput

0.479

High

902043

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.479

High

905105

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

907568

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.479

High

971031

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

1047093

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

1

Small-scale

0.479

High

1057473

SOX4
Transcription factor SOX-4

1

7

High-throughput

0.479

High

1067687

EP300
Histone acetyltransferase p300

1

3

High-throughput

0.479

High

1092227

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

1107173

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1114203

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1128106

DHX8
ATP-dependent RNA helicase DHX8

1

1

High-throughput

0.479

High

1138017

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.479

High

1201959

BRDT
Bromodomain testis-specific protein

1

6

High-throughput

0.479

High

1233213

THOC7
THO complex subunit 7

1

2

High-throughput

0.479

High

1235678

NIPBL
Nipped-B-like protein

1

5

High-throughput

0.479

High

1255393

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

1271839

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.479

High

1290701

ZCH18
Zinc finger CCCH domain-containing protein 18

1

6

High-throughput

0.479

High

1311847

DHX40
Probable ATP-dependent RNA helicase DHX40

1

1

High-throughput

0.479

High

1313403

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1352727

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1364242

TOPB1
DNA topoisomerase 2-binding protein 1

1

2

High-throughput

0.479

High

1367190

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1380141

FBXW7
F-box/WD repeat-containing protein 7

1

4

High-throughput

0.479

High

1387543

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

5

High-throughput

0.479

High

1393661

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1404737

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

1407853

ANM1
Protein arginine N-methyltransferase 1

1

4

High-throughput

0.479

High

1414551

DDX23
Probable ATP-dependent RNA helicase DDX23

1

4

High-throughput

0.479

High

1417811

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

1417813

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1417814

SOX17
Transcription factor SOX-17

1

6

High-throughput

0.479

High

1417815

WDR76
WD repeat-containing protein 76

1

5

High-throughput

0.479

High

1417818

ANLN
Anillin

1

1

High-throughput

0.479

High

1417819

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

1417824

LUZP4
Leucine zipper protein 4

1

1

Small-scale

0.479

High

1417826

NXF1
Nuclear RNA export factor 1

1

2

High-throughput

0.479

High

1417828

TEKT2
Tektin-2

1

2

High-throughput

0.479

High

1417835

CC14A
Dual specificity protein phosphatase CDC14A

1

1

High-throughput

0.479

High

1417836

FBW1A
F-box/WD repeat-containing protein 1A

1

5

High-throughput

0.479

High

1417840

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

1417841

CHTOP
Chromatin target of PRMT1 protein

1

1

High-throughput

0.479

High

1311779

HOMEZ
Homeobox and leucine zipper protein Homez

1

0

High-throughput

0.460

High

138762

IMA4
Importin subunit alpha-4

1

0

High-throughput

0.458

High

159833

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

340396

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.458

High

378518

IL1A
Interleukin-1 alpha

1

0

Small-scale

0.458

High

459333

CATL1
Procathepsin L

1

0

High-throughput

0.458

High

848299

MAGA3
Melanoma-associated antigen 3

1

0

Small-scale

0.458

High

925679

IST1
IST1 homolog

1

0

High-throughput

0.458

High

927125

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

976533

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

1132032

STAT4
Signal transducer and activator of transcription 4

1

0

High-throughput

0.458

High

1133409

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

1

0

High-throughput

0.458

High

1149981

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.458

High

1161646

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1238474

ZN746
Zinc finger protein 746

1

0

High-throughput

0.458

High

1289598

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1314398

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

1372190

MED12
Mediator of RNA polymerase II transcription subunit 12

1

0

High-throughput

0.458

High

1387329

OTUB2
Ubiquitin thioesterase OTUB2

1

0

Small-scale

0.458

High

1390530

CDCA5
Sororin

1

0

High-throughput

0.458

High

1405559

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

1417820

RNC
Ribonuclease 3

1

0

High-throughput

0.458

High

1417821

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.458

High

1417843

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

931891

EPHA5
Ephrin type-A receptor 5

1

4

High-throughput

0.457

High

1049198

RON
Macrophage-stimulating protein receptor

1

5

High-throughput

0.457

High

1147420

EPHA7
Ephrin type-A receptor 7

1

4

High-throughput

0.457

High

430323

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

530333

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

1203248

ODFP2
Outer dense fiber protein 2

1

1

High-throughput

0.445

High

1417830

DDX41
Probable ATP-dependent RNA helicase DDX41

1

3

High-throughput

0.445

High

1417831

OSGI1
Oxidative stress-induced growth inhibitor 1

1

1

High-throughput

0.439

High

75721

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

106597

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

1360928

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

1417809

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

1417834

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.437

High

887199

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.408

High

69548

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.407

High

1289398

URP2
Fermitin family homolog 3

1

0

High-throughput

0.279

Low

1356808

NEUFC
Neuferricin

1

0

High-throughput

0.279

Low

1403976

SCN2A
Sodium channel protein type 2 subunit alpha

1

0

High-throughput

0.279

Low

1417823

USE1
Vesicle transport protein USE1

1

0

High-throughput

0.279

Low

180036

BET1
BET1 homolog

1

0

High-throughput

0.249

Low

488856

FURIN
Furin

1

0

High-throughput

0.249

Low

774598

BASI
Basigin

1

0

High-throughput

0.249

Low

1031531

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.249

Low

1241341

CH082
UPF0598 protein C8orf82

1

0

High-throughput

0.249

Low

1214187

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025