HitPredict

Interactor 1: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33306668
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 496 Hs			1 504
+	Hs
		1281473 FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		1288388 SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		1281292 FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		1309163 TBL1Y_HUMAN (99-430): 2.64e-70: 234: 16.20		TBL1R_HUMAN (134-466): 1.2e-76: 251: 14.57
+	Dm
		1358859 FBXW7_DROME (20-496): 6.04e-89: 298: 17.46		WDS_DROME (93-337): 9.07e-43: 157: 15.23
+	Hs
		903418 FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		792935 LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68		LIS1_HUMAN (302-504): 3.93e-56: 194: 19.11
+	Mm
		925836 LIS1_MOUSE (309-495): 5.38e-53: 185: 19.68		LIS1_MOUSE (302-504): 2.99e-56: 194: 19.11
+	Hs
		903551 NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		1346954 NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86
+	Hs
		197071 SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84
+	Hs
		1240442 POC1B_HUMAN (31-259): 4.34e-30: 124: 13.19		POC1A_HUMAN (88-377): 5.18e-64: 215: 20.68
+	Hs
		792949 LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		903428 SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Sp
		999842 TUP12_SCHPO (346-495): 7.82e-30: 125: 20.89		TUP11_SCHPO (70-340): 1.86e-44: 167: 13.78
+	Hs
		196984 WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84
+	Hs
		903077 WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		903349 WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35		WDR5B_HUMAN (89-333): 1.53e-40: 150: 16.60
+	Hs
		793026 LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68		KTNB1_HUMAN (282-504): 4.25e-12: 70.5: 27.07