Protein: MKS3
Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67)

Gene: MKS3, TMEM67
Organism: Homo sapiens
Interactions: 128
UniProt ID: Q5HYA8

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0005813 - centrosome
GO:0010826 - negative regulation of centrosome duplication
GO:0030659 - cytoplasmic vesicle membrane
GO:0031005 - filamin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1126142

AT1B4
Protein ATP1B4

3

1

High-throughput

0.609

High

1126123

TECT2
Tectonic-2

2

0

High-throughput

0.602

High

514397

PSPC
Surfactant protein C

2

0

Small-scale

0.585

High

328127

SG1D1
Secretoglobin family 1D member 1

2

1

High-throughput

0.574

High

1126101

TM11B
Transmembrane protease serine 11B

2

2

High-throughput

0.574

High

1126124

TAFA4
Chemokine-like protein TAFA-4

2

2

High-throughput

0.574

High

161080

CLGN
Calmegin

1

1

High-throughput

0.536

High

409522

HEPS
Serine protease hepsin

1

2

High-throughput

0.536

High

654403

CALX
Calnexin

1

1

High-throughput

0.536

High

1092756

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

1126133

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

1126143

HYOU1
Hypoxia up-regulated protein 1

1

0

High-throughput

0.513

High

354709

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

5

High-throughput

0.489

High

354848

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

6

High-throughput

0.489

High

393454

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

High-throughput

0.489

High

410567

CD1A
T-cell surface glycoprotein CD1a

1

4

High-throughput

0.489

High

488251

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

1

High-throughput

0.489

High

550281

CD1E
T-cell surface glycoprotein CD1e, membrane-associated

1

4

High-throughput

0.489

High

570334

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

1

High-throughput

0.489

High

656366

DMB
HLA class II histocompatibility antigen, DM beta chain

1

4

High-throughput

0.489

High

657882

CYTD
Cystatin-D

1

1

High-throughput

0.489

High

661094

CD1B
T-cell surface glycoprotein CD1b

1

4

High-throughput

0.489

High

945201

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

6

High-throughput

0.489

High

1109740

CC50B
Cell cycle control protein 50B

1

1

High-throughput

0.489

High

1126096

IGFL1
Insulin growth factor-like family member 1

1

1

High-throughput

0.489

High

1126097

IGFL3
Insulin growth factor-like family member 3

1

1

High-throughput

0.489

High

1126098

SG1D4
Secretoglobin family 1D member 4

1

1

High-throughput

0.489

High

1126100

TAFA5
Chemokine-like protein TAFA-5

1

2

High-throughput

0.489

High

1126104

TAFA2
Chemokine-like protein TAFA-2

1

2

High-throughput

0.489

High

1126127

WFDC6
WAP four-disulfide core domain protein 6

1

1

High-throughput

0.489

High

1126132

CST11
Cystatin-11

1

1

High-throughput

0.489

High

1126137

CC50A
Cell cycle control protein 50A

1

1

High-throughput

0.489

High

1126144

ST14
Suppressor of tumorigenicity 14 protein

1

2

High-throughput

0.489

High

1126141

UBQL1
Ubiquilin-1

1

1

High-throughput

0.481

High

913288

PRS10
26S proteasome regulatory subunit 10B

1

2

High-throughput

0.479

High

275023

RENR
Renin receptor

1

0

High-throughput

0.458

High

299911

ERLN2
Erlin-2

1

0

High-throughput

0.458

High

390274

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

438774

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.458

High

502184

BIP
Endoplasmic reticulum chaperone BiP

1

0

Small-scale

0.458

High

823593

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

1

0

High-throughput

0.458

High

847501

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

894859

SPCS3
Signal peptidase complex subunit 3

1

0

High-throughput

0.458

High

895112

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.458

High

931529

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

0

High-throughput

0.458

High

990479

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

1041730

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1062444

SPCS2
Signal peptidase complex subunit 2

1

0

High-throughput

0.458

High

1062536

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.458

High

1079818

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.458

High

1114022

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

0

High-throughput

0.458

High

1126102

VRK2
Serine/threonine-protein kinase VRK2

1

0

High-throughput

0.458

High

1126105

TM199
Transmembrane protein 199

1

0

High-throughput

0.458

High

1126107

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1126110

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.458

High

1126111

HM13
Minor histocompatibility antigen H13

1

0

High-throughput

0.458

High

1126117

UBXN4
UBX domain-containing protein 4

1

0

High-throughput

0.458

High

1126120

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.458

High

1126130

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1126131

MAGT1
Magnesium transporter protein 1

1

0

High-throughput

0.458

High

1126134

SEC12
Guanine nucleotide-exchange factor SEC12

1

0

High-throughput

0.458

High

1126139

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.458

High

205479

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

572982

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.437

High

798687

PRS6B
26S proteasome regulatory subunit 6B

1

2

High-throughput

0.437

High

907056

PRS8
26S proteasome regulatory subunit 8

1

2

High-throughput

0.437

High

1027686

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.437

High

1126126

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

1

High-throughput

0.437

High

354958

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

4

High-throughput

0.407

High

310293

LYPD3
Ly6/PLAUR domain-containing protein 3

3

0

High-throughput

0.347

High

645802

CD27
CD27 antigen

3

0

High-throughput

0.347

High

1069922

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

0

High-throughput

0.347

High

237366

ISK4
Serine protease inhibitor Kazal-type 4

2

0

High-throughput

0.328

High

887039

DEF1
Neutrophil defensin 1

2

0

High-throughput

0.328

High

1126093

DB121
Beta-defensin 121

2

0

High-throughput

0.328

High

1126099

LYZL2
Lysozyme-like protein 2

2

0

High-throughput

0.328

High

1126103

S22A9
Organic anion transporter 7

2

0

High-throughput

0.328

High

1126125

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

2

0

High-throughput

0.328

High

1126129

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

0

High-throughput

0.328

High

1126135

NRN1
Neuritin

2

0

High-throughput

0.328

High

1126114

SYNE2
Nesprin-2

1

0

Small-scale

0.292

High

61691

CDHR4
Cadherin-related family member 4

1

0

High-throughput

0.279

Low

131903

UPK2
Uroplakin-2

1

0

High-throughput

0.279

Low

314477

APOM
Apolipoprotein M

1

0

High-throughput

0.279

Low

319568

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

435956

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.279

Low

474720

CFC1
Cryptic protein

1

0

High-throughput

0.279

Low

516045

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.279

Low

540297

GPIX
Platelet glycoprotein IX

1

0

High-throughput

0.279

Low

554320

MUC1
Mucin-1

1

0

High-throughput

0.279

Low

702231

CD70
CD70 antigen

1

0

High-throughput

0.279

Low

802331

5HT3A
5-hydroxytryptamine receptor 3A

1

0

High-throughput

0.279

Low

960723

NDP
Norrin

1

0

High-throughput

0.279

Low

1103713

DB136
Defensin beta 136

1

0

High-throughput

0.279

Low

1103734

DB135
Beta-defensin 135

1

0

High-throughput

0.279

Low

1103756

DB110
Beta-defensin 110

1

0

High-throughput

0.279

Low

1115461

CLM2
CMRF35-like molecule 2

1

0

High-throughput

0.279

Low

1126095

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

1126106

DB123
Beta-defensin 123

1

0

High-throughput

0.279

Low

1126108

SIGL1
SIGLEC family-like protein 1

1

0

High-throughput

0.279

Low

1126113

PATE1
Prostate and testis expressed protein 1

1

0

High-throughput

0.279

Low

1126115

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

1

0

High-throughput

0.279

Low

1126116

CLC2B
C-type lectin domain family 2 member B

1

0

High-throughput

0.279

Low

1126121

ESPB1
Epididymal sperm-binding protein 1

1

0

High-throughput

0.279

Low

1126122

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.279

Low

1126128

TM2D3
TM2 domain-containing protein 3

1

0

High-throughput

0.279

Low

1126136

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.279

Low

1126140

BTNL2
Butyrophilin-like protein 2

1

0

High-throughput

0.279

Low

394872

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.268

Low

130923

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.249

Low

170859

PGRC2
Membrane-associated progesterone receptor component 2

1

0

High-throughput

0.249

Low

178920

TOX3
TOX high mobility group box family member 3

1

0

High-throughput

0.249

Low

315373

NSA2
Ribosome biogenesis protein NSA2 homolog

1

0

High-throughput

0.249

Low

657364

ABCD3
ATP-binding cassette sub-family D member 3

1

0

High-throughput

0.249

Low

677988

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.249

Low

815782

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

0

High-throughput

0.249

Low

846623

MMP15
Matrix metalloproteinase-15

1

0

High-throughput

0.249

Low

874113

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

High-throughput

0.249

Low

977413

KCNC4
Potassium voltage-gated channel subfamily C member 4

1

0

High-throughput

0.249

Low

1057944

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.249

Low

1126094

TOIP1
Torsin-1A-interacting protein 1

1

0

High-throughput

0.249

Low

1126109

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

1126112

DDX54
ATP-dependent RNA helicase DDX54

1

0

High-throughput

0.249

Low

1126118

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.249

Low

1126119

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.249

Low

1126138

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

209243

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.232

Low

1103764

DB109
Putative beta-defensin 109B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024