HitPredict

Interactor 1: PCDA7 (Q9UN72)
Protocadherin alpha-7 (PCDH-alpha-7)
Gene: PCDHA7

Interactor 2: PCDAC (Q9UN75)
Protocadherin alpha-12 (PCDH-alpha-12)
Gene: PCDHA12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cadherin~Cadherin, Cadherin~Cadherin_2
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules GO:0007399 - nervous system development
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 937 Hs			1 941
+	Hs
		1357403 PCDA7_HUMAN (1-937): 0: 1066: 100.00		PCDA4_HUMAN (1-941): 0: 1042: 81.10
+	Hs
		1357407 PCDA7_HUMAN (1-937): 0: 1066: 100.00		PCDA2_HUMAN (1-941): 0: 1036: 80.49
+	Hs
		1357412 PCDA4_HUMAN (1-937): 0: 1047: 85.32		PCDAC_HUMAN (1-941): 0: 1034: 100.00
+	Hs
		1357419 PCDA4_HUMAN (1-937): 0: 1047: 85.32		PCDA1_HUMAN (25-941): 0: 1025: 80.02
+	Hs
		1357387 PCDA4_HUMAN (1-937): 0: 1047: 85.32		PCDGK_HUMAN (27-889): 0: 556: 38.15
+	Hs
		1357406 PCDA7_HUMAN (1-937): 0: 1066: 100.00		PCDA8_HUMAN (2-446): 3.37e-95: 323: 24.19
+	Hs
		1357417 PCDA4_HUMAN (1-937): 0: 1047: 85.32		PCDAB_HUMAN (2-446): 9.32e-100: 335: 25.76
+	Hs
		1357414 PCDA4_HUMAN (1-937): 0: 1047: 85.32		PCDGA_HUMAN (2-447): 1.19e-98: 332: 25.33
+	Hs
		1357408 PCDA7_HUMAN (1-937): 0: 1066: 100.00		PCDAA_HUMAN (2-446): 1.49e-90: 310: 25.97
+	Hs
		1378052 PCDA2_HUMAN (1-937): 0: 1049: 80.17		PCDA8_HUMAN (2-446): 3.37e-95: 323: 24.19
+	Hs
		1357416 PCDA4_HUMAN (1-937): 0: 1047: 85.32		PCDA8_HUMAN (2-446): 3.37e-95: 323: 24.19
+	Hs
		1357405 PCDA7_HUMAN (1-937): 0: 1066: 100.00		PCDA9_HUMAN (2-446): 4.5e-88: 303: 24.09
+	Hs
		1378053 PCDAD_HUMAN (1-937): 0: 1041: 80.84		PCDA8_HUMAN (2-446): 3.37e-95: 323: 24.19
+	Hs
		1378058 PCDA5_HUMAN (24-937): 0: 1052: 83.26		PCDAA_HUMAN (2-446): 1.49e-90: 310: 25.97
+	Hs
		1378062 PCDA2_HUMAN (1-937): 0: 1049: 80.17		PCDAA_HUMAN (2-446): 1.49e-90: 310: 25.97
+	Hs
		1357418 PCDA4_HUMAN (1-937): 0: 1047: 85.32		PCDAA_HUMAN (2-446): 1.49e-90: 310: 25.97
+	Hs
		1378063 PCDAD_HUMAN (1-937): 0: 1041: 80.84		PCDAA_HUMAN (2-446): 1.49e-90: 310: 25.97
+	Hs
		1357415 PCDA4_HUMAN (1-937): 0: 1047: 85.32		PCDA9_HUMAN (2-446): 4.5e-88: 303: 24.09