HitPredict - High confidence protein-protein interactions

Interactor 1: TNF18 (Q9UNG2)
Tumor necrosis factor ligand superfamily member 18 (Activation-inducible TNF-related ligand) (AITRL) (Glucocorticoid-induced TNF-related ligand) (hGITRL)
Gene: TNFSF18

Interactor 2: TNF18 (Q9UNG2)
Tumor necrosis factor ligand superfamily member 18 (Activation-inducible TNF-related ligand) (AITRL) (Glucocorticoid-induced TNF-related ligand) (hGITRL)
Gene: TNFSF18

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.644

Property	Details
Experiments	18040044, 18378892
Identification Methods	molecular sieving, cosedimentation in solution, x-ray crystallography, cross-linking study, comigration in sds page
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002250 - adaptive immune response GO:0002309 - T cell proliferation involved in immune response GO:0002687 - positive regulation of leukocyte migration GO:0005102 - signaling receptor binding GO:0005125 - cytokine activity and 12 others more... GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0007267 - cell-cell signaling GO:0009986 - cell surface GO:0032813 - tumor necrosis factor receptor superfamily binding GO:0033209 - tumor necrosis factor-mediated signaling pathway GO:0042129 - regulation of T cell proliferation GO:0042531 - positive regulation of tyrosine phosphorylation of STAT protein GO:0043066 - negative regulation of apoptotic process GO:0045785 - positive regulation of cell adhesion GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	177
Hs

1	177

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Last updated: 15 Jul 2024