HitPredict

Interactor 1: ABCG2 (Q9UNQ0)
Broad substrate specificity ATP-binding cassette transporter ABCG2 (EC 7.6.2.2) (ATP-binding cassette sub-family G member 2) (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338)
Gene: ABCG2

Interactor 2: ABCG2 (Q9UNQ0)
Broad substrate specificity ATP-binding cassette transporter ABCG2 (EC 7.6.2.2) (ATP-binding cassette sub-family G member 2) (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338)
Gene: ABCG2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.934

The method score is based on:

Property Details
Experiments 17098188, 19506252, 20399185, 28554189, 29610494, 16870176
Identification Methods 3D electron microscopy, blue native page, comigration in non denaturing gel electrophoresis, electron microscopy, comigration in sds page, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ABC2_membrane~ABC2_membrane, ABC2_membrane~ABC_tran, ABC2_membrane_7~ABC2_membrane_7, ABC2_membrane_7~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0008514 - organic anion transmembrane transporter activity
GO:0008559 - ABC-type xenobiotic transporter activity
and 26 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 655
Hs

1 655
+ Hs
+ Hs
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+ At
+ At
+ At
+ At
+ At
+ Zm
+ Dm
+ Hs
+ Zm
+ Hs

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Last updated: 15 Jul 2024