HitPredict

Interactor 1: LHX6 (Q9UPM6)
LIM/homeobox protein Lhx6 (LIM homeobox protein 6) (LIM/homeobox protein Lhx6.1)
Gene: LHX6

Interactor 2: SATB2 (Q9UPW6)
DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2)
Gene: SATB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CUT~Homeodomain, Homeodomain~Homeodomain
Common GO terms	GO:0000785 - chromatin GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 363 Hs			1 733
+	Hs
		822692 LHX1_HUMAN (70-362): 1.71e-52: 180: 26.65		SATB2_HUMAN (1-733): 0: 1220: 100.00
+	Hs
		839846 LHX2_HUMAN (27-199): 1.4e-47: 167: 34.46		SATB2_HUMAN (1-733): 0: 1220: 100.00
+	Hs
		1281203 LHX4_HUMAN (3-124): 3.11e-19: 90: 11.81		SATB2_HUMAN (1-733): 0: 1220: 100.00
+	Hs
		1354253 LHX3_HUMAN (4-124): 2.09e-18: 87.7: 14.52		SATB2_HUMAN (1-733): 0: 1220: 100.00
+	Hs
		822626 LHX1_HUMAN (70-362): 1.71e-52: 180: 26.65		SATB1_HUMAN (1-718): 0: 1045: 60.82
+	Hs
		839731 LHX2_HUMAN (27-199): 1.4e-47: 167: 34.46		SATB1_HUMAN (1-718): 0: 1045: 60.82
+	Hs
		966988 LHX4_HUMAN (3-124): 3.11e-19: 90: 11.81		SATB1_HUMAN (1-718): 0: 1045: 60.82