HitPredict

Interactor 1: DYN3 (Q9UQ16)
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
Gene: DNM3

Interactor 2: SNX5 (Q9Y5X3)
Sorting nexin-5
Gene: SNX5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PX
Common GO terms	GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 869 Hs			1 404
+	Hs
		1357510 DYN3_HUMAN (1-869): 0: 1080: 100.00		SNX6_HUMAN (10-404): 5.06e-109: 327: 64.81
+	Hs
		240458 DYN3_HUMAN (1-869): 0: 1080: 100.00		SNX2_HUMAN (19-403): 8.5e-91: 284: 24.15
+	Hs
		1040534 DYN3_HUMAN (1-869): 0: 1080: 100.00		SNX1_HUMAN (5-403): 5.87e-88: 277: 21.23
+	Hs
		1261052 DYN3_HUMAN (1-869): 0: 1080: 100.00		SNX33_HUMAN (1-403): 2.74e-75: 246: 13.48
+	Hs
		240366 DYN2_HUMAN (1-869): 0: 1041: 79.21		SNX2_HUMAN (19-403): 8.5e-91: 284: 24.15
+	Hs
		1357820 DYN3_HUMAN (1-869): 0: 1080: 100.00		SNX9_HUMAN (27-401): 1.33e-71: 237: 14.98
+	Hs
		840772 DYN2_HUMAN (1-869): 0: 1041: 79.21		SNX33_HUMAN (1-403): 2.74e-75: 246: 13.48
+	Hs
		983396 DYN1_HUMAN (1-852): 0: 1035: 78.56		SNX33_HUMAN (1-403): 2.74e-75: 246: 13.48
+	Hs
		840879 DYN2_HUMAN (1-869): 0: 1041: 79.21		SNX9_HUMAN (27-401): 1.33e-71: 237: 14.98
+	Hs
		2824 A0A0D9SFE4_HUMAN (1-869): 0: 1038: 77.96		SNX9_HUMAN (27-401): 1.33e-71: 237: 14.98
+	Hs
		983421 DYN1_HUMAN (1-852): 0: 1035: 78.56		SNX9_HUMAN (27-401): 1.33e-71: 237: 14.98
+	Hs
		840797 DYN2_HUMAN (1-869): 0: 1041: 79.21		SNX18_HUMAN (18-362): 5.85e-67: 225: 13.64
+	Ce
		760504 DYN1_CAEEL (3-815): 0: 947: 62.09		LST4_CAEEL (30-402): 6.2e-63: 213: 13.81