HitPredict

Interactor 1: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Interactor 2: E41L3 (Q9Y2J2)
Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]
Gene: EPB41L3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	24366813, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2752 Hs			1 1087
+	Hs
		663994 SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00		PTN4_HUMAN (91-695): 1.96e-140: 448: 29.55
+	Hs
		640290 SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00		PTN3_HUMAN (90-701): 3.39e-122: 399: 23.67
+	Hs
		1301010 CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98		E41L3_HUMAN (1-1087): 0: 752: 100.00
+	Hs
		1244255 BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13		E41L3_HUMAN (1-1087): 0: 752: 100.00
+	Hs
		965178 ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23		E41L3_HUMAN (1-1087): 0: 752: 100.00
+	Hs
		204759 SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00		E41L2_HUMAN (583-1087): 1.39e-44: 177: 32.64
+	Hs
		1331061 SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00		E41L1_HUMAN (631-1084): 9.44e-23: 107: 21.33
+	Hs
		1301019 CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98		FARP1_HUMAN (73-662): 1.4e-114: 381: 28.31
+	Hs
		1329247 TARA_HUMAN (1540-2752): 1.5e-31: 138: 11.50		E41L5_HUMAN (74-826): 2.96e-137: 433: 25.07
+	Hs
		1244244 BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13		E41L5_HUMAN (74-826): 2.96e-137: 433: 25.07
+	Hs
		547213 TARA_HUMAN (1540-2752): 1.5e-31: 138: 11.50		EZRI_HUMAN (106-636): 1.38e-120: 384: 22.28
+	Hs
		547010 ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23		EZRI_HUMAN (106-636): 1.38e-120: 384: 22.28
+	Hs
		297842 K0754_HUMAN (864-1413): 2.27e-10: 69.1: 16.44		E41LA_HUMAN (107-555): 5.64e-117: 378: 32.54
+	Hs
		965179 ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23		FARP1_HUMAN (73-662): 1.4e-114: 381: 28.31
+	Hs
		204725 CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98		E41L2_HUMAN (583-1087): 1.39e-44: 177: 32.64
+	Hs
		505670 CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98		EPB41_HUMAN (701-1083): 3.49e-41: 166: 33.33
+	Dm
		113976 M9PB30_DROME (2292-2752): 2.57e-14: 82: 11.45		M9PB30_DROME (409-1024): 5.93e-73: 269: 16.72