HitPredict

Interactor 1: NXT1 (Q9V3H8)
NTF2-related export protein (p15)
Gene: NXT1

Interactor 2: NXF2 (Q9VV73)
Nuclear RNA export factor 2
Gene: NXF2

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	31398345, 31368590, 31570835, 31384064, 31219034
Identification Methods	affinity chromatography technology, pull down, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016973 - poly(A)+ mRNA export from nucleus GO:0017053 - transcription repressor complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 133 Dm			1 841
+	Hs
		1342974 NXT2_HUMAN (4-132): 2.6e-48: 153: 42.11		NXF1_HUMAN (305-840): 0: 681: 20.51
+	Hs
		1354351 NXT1_HUMAN (4-132): 2.16e-48: 153: 41.35		NXF1_HUMAN (305-840): 0: 681: 20.51
+	Hs
		1030533 G3BP1_HUMAN (10-132): 1.71e-42: 147: 20.59		NXF1_HUMAN (305-840): 0: 681: 20.51
+	Mm
		1113012 NXT2_MOUSE (1-132): 9.39e-49: 154: 39.71		NXF1_MOUSE (305-840): 0: 667: 20.15
+	Mm
		1307776 NXT1_MOUSE (4-132): 3.32e-48: 153: 40.60		NXF1_MOUSE (305-840): 0: 667: 20.15
+	Hs
		903854 NTF2_HUMAN (13-130): 1.74e-40: 133: 27.50		NXF1_HUMAN (305-840): 0: 681: 20.51
+	Hs
		1326869 NXT2_HUMAN (4-132): 2.6e-48: 153: 42.11		NXF2_HUMAN (305-840): 0: 649: 20.15
+	Hs
		1326878 NXT1_HUMAN (4-132): 2.16e-48: 153: 41.35		NXF2_HUMAN (305-840): 0: 649: 20.15
+	Mm
		1113011 NXT2_MOUSE (1-132): 9.39e-49: 154: 39.71		Q8R499_MOUSE (304-840): 0: 538: 17.67
+	Mm
		1246891 NXT1_MOUSE (4-132): 3.32e-48: 153: 40.60		Q8R499_MOUSE (304-840): 0: 538: 17.67
+	Hs
		1330910 NXT2_HUMAN (4-132): 2.6e-48: 153: 42.11		NXF3_HUMAN (305-796): 5.68e-171: 506: 16.01
+	Hs
		1330913 NXT1_HUMAN (4-132): 2.16e-48: 153: 41.35		NXF3_HUMAN (305-796): 5.68e-171: 506: 16.01
+	Mm
		1113010 NXT2_MOUSE (1-132): 9.39e-49: 154: 39.71		Q4ZGD9_MOUSE (305-841): 4.01e-165: 492: 17.85
+	Mm
		1119186 NXT1_MOUSE (4-132): 3.32e-48: 153: 40.60		Q4ZGD9_MOUSE (305-841): 4.01e-165: 492: 17.85
+	Dm
		1353476 NXT1_DROME (1-133): 1.31e-46: 148: 100.00		NXF1_DROME (305-840): 2.32e-159: 481: 20.26
+	Ce
		1353757 NXT1_CAEEL (2-132): 5.61e-42: 137: 28.79		NXF1_CAEEL (339-841): 1.07e-140: 432: 20.04
+	Dm
		1214855 NXT1_DROME (1-133): 1.31e-46: 148: 100.00		Q8IQK4_DROME (321-840): 1.19e-111: 355: 18.35
+	Ce
		1353758 NXT1_CAEEL (2-132): 5.61e-42: 137: 28.79		NXF2_CAEEL (418-765): 1.22e-98: 314: 22.95