HitPredict

Interactor 1: RB40A (Q8WXH6)
Ras-related protein Rab-40A (EC 3.6.5.2) (SOCS box-containing protein RAR2A) (Protein Rar-2)
Gene: RAB40A

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cullin~SOCS_box
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 277 Hs			1 780
+	Hs
		1086742 RB40B_HUMAN (1-277): 2.97e-101: 298: 87.41		CUL5_HUMAN (1-780): 0: 791: 100.00
+	Hs
		501778 RB40L_HUMAN (1-277): 6.11e-101: 297: 97.12		CUL5_HUMAN (1-780): 0: 791: 100.00
+	Xl
		67969 Q5XHF6_XENLA (1-277): 9.45e-94: 279: 72.03		A7VK04_XENLA (1-780): 0: 792: 98.33
+	Hs
		1371840 RB40C_HUMAN (1-277): 4.24e-92: 275: 73.31		CUL5_HUMAN (1-780): 0: 791: 100.00
+	Mm
		1354091 RB40C_MOUSE (1-277): 1.36e-91: 274: 73.67		CUL5_MOUSE (1-780): 0: 785: 98.46
+	Hs
		902188 RAB13_HUMAN (7-203): 3.76e-88: 262: 39.39		CUL3_HUMAN (8-780): 0: 753: 22.96
+	Hs
		1114263 RAB1B_HUMAN (7-197): 1e-82: 248: 34.83		CUL3_HUMAN (8-780): 0: 753: 22.96
+	Hs
		1115049 RAB1B_HUMAN (7-197): 1e-82: 248: 34.83		CUL4A_HUMAN (16-780): 0: 743: 24.48
+	Hs
		947466 RAB15_HUMAN (9-179): 2.76e-46: 155: 44.19		CUL3_HUMAN (8-780): 0: 753: 22.96
+	Hs
		956716 RAB10_HUMAN (9-175): 1.39e-43: 148: 43.45		CUL3_HUMAN (8-780): 0: 753: 22.96