Interactor 1: PLK4 (O00444)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)
Gene: PLK4
Interactor 2: STIL (Q15468)
SCL-interrupting locus protein (TAL-1-interrupting locus protein)
Gene: STIL
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.76 | 0.60 | 0.678 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24613305, 27872092, 26188084 |
| Identification Methods | proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, pull down, protein kinase assay, isothermal titration calorimetry |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0046601 - positive regulation of centriole replication GO:0120099 - procentriole replication complex |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
