Protein: K2C6C
Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK-6C) (Cytokeratin-6E) (CK-6E) (Keratin K6h) (Keratin-6C) (K6C) (Type-II keratin Kb12)

Gene: K2C6C, KRT6C
Organism: Homo sapiens
Interactions: 77
UniProt ID: P48668

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0030280 - structural constituent of skin epidermis
GO:0031424 - keratinization
GO:0045095 - keratin filament

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

408759

K1C18
Keratin, type I cytoskeletal 18

4

20

High-throughput

0.890

High

280959

KRT38
Keratin, type I cuticular Ha8

3

20

High-throughput

0.871

High

821663

K1H1
Keratin, type I cuticular Ha1

3

20

High-throughput

0.871

High

821668

K1C40
Keratin, type I cytoskeletal 40

3

20

High-throughput

0.871

High

580004

K1C15
Keratin, type I cytoskeletal 15

2

20

High-throughput

0.817

High

280544

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.783

High

280782

KRT36
Keratin, type I cuticular Ha6

2

20

High-throughput

0.783

High

280861

KRT37
Keratin, type I cuticular Ha7

2

20

High-throughput

0.783

High

359315

K1C14
Keratin, type I cytoskeletal 14

2

20

High-throughput

0.783

High

444336

K1C19
Keratin, type I cytoskeletal 19

2

20

High-throughput

0.783

High

445017

K1C16
Keratin, type I cytoskeletal 16

2

20

High-throughput

0.783

High

821657

KT33B
Keratin, type I cuticular Ha3-II

2

20

High-throughput

0.783

High

821665

K1C24
Keratin, type I cytoskeletal 24

2

20

High-throughput

0.783

High

821673

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.783

High

821674

K1C26
Keratin, type I cytoskeletal 26

2

20

High-throughput

0.783

High

821675

K1C25
Keratin, type I cytoskeletal 25

2

20

High-throughput

0.783

High

821680

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.783

High

531456

K1C13
Keratin, type I cytoskeletal 13

2

20

High-throughput

0.754

High

821683

KIFC3
Kinesin-like protein KIFC3

3

9

High-throughput

0.675

High

49559

A1A4E9
Keratin 13

1

20

High-throughput

0.665

High

821672

K1C28
Keratin, type I cytoskeletal 28

1

20

High-throughput

0.621

High

821648

K1C17
Keratin, type I cytoskeletal 17

1

20

High-throughput

0.618

High

821685

TRI54
Tripartite motif-containing protein 54

3

20

High-throughput

0.616

High

821666

LARP7
La-related protein 7

2

10

High-throughput

0.584

High

821649

ACTN3
Alpha-actinin-3

2

0

High-throughput

0.580

High

528760

CFTR
Cystic fibrosis transmembrane conductance regulator

1

16

High-throughput

0.536

High

821653

CUL1
Cullin-1

1

20

High-throughput

0.536

High

821654

CUL2
Cullin-2

1

20

High-throughput

0.536

High

821681

CSN5
COP9 signalosome complex subunit 5

1

14

High-throughput

0.536

High

821650

GOGA2
Golgin subfamily A member 2

1

7

High-throughput

0.523

High

821692

TFP11
Tuftelin-interacting protein 11

1

4

High-throughput

0.523

High

821662

PLEC
Plectin

1

16

High-throughput

0.515

High

821651

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

2

High-throughput

0.494

High

456825

FURIN
Furin

1

0

High-throughput

0.493

High

821689

P63
Tumor protein 63

1

7

Small-scale

0.489

High

124797

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

9

Small-scale

0.479

High

129243

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.479

High

176407

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

7

High-throughput

0.479

High

325658

LATS1
Serine/threonine-protein kinase LATS1

1

4

High-throughput

0.479

High

453213

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

6

High-throughput

0.479

High

610295

CBL
E3 ubiquitin-protein ligase CBL

1

10

High-throughput

0.479

High

821659

CUL7
Cullin-7

1

4

High-throughput

0.479

High

821660

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

821661

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

14

High-throughput

0.479

High

821669

RICTR
Rapamycin-insensitive companion of mTOR

1

5

High-throughput

0.479

High

821684

ACE2
Angiotensin-converting enzyme 2

1

5

High-throughput

0.479

High

821688

RN208
RING finger protein 208

1

20

Small-scale

0.479

High

739

MEIKN
Meiosis-specific kinetochore protein

1

1

High-throughput

0.470

High

821646

TPIS
Triosephosphate isomerase

1

0

Small-scale

0.458

High

821694

FBX7
F-box only protein 7

1

0

High-throughput

0.458

High

306027

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.445

High

319759

HERC2
E3 ubiquitin-protein ligase HERC2

1

2

High-throughput

0.445

High

719412

MERL
Merlin

1

1

High-throughput

0.445

High

821647

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

821676

KIBRA
Protein KIBRA

1

18

High-throughput

0.445

High

821677

PALS1
Protein PALS1

1

3

High-throughput

0.445

High

821679

INADL
InaD-like protein

1

5

High-throughput

0.445

High

821687

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

821690

PDLI7
PDZ and LIM domain protein 7

1

1

High-throughput

0.445

High

821691

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.445

High

260483

PITX3
Pituitary homeobox 3

1

3

Small-scale

0.437

High

303013

HEXI1
Protein HEXIM1

1

17

High-throughput

0.437

High

595981

EFNA1
Ephrin-A1

1

20

High-throughput

0.437

High

821644

EFNA3
Ephrin-A3

1

20

High-throughput

0.437

High

821645

EFNA4
Ephrin-A4

1

20

High-throughput

0.437

High

821652

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

18

High-throughput

0.437

High

821655

DX39B
Spliceosome RNA helicase DDX39B

1

18

High-throughput

0.437

High

821658

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

18

High-throughput

0.437

High

821664

EZH2
Histone-lysine N-methyltransferase EZH2

1

8

High-throughput

0.437

High

821670

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

821671

MEPCE
7SK snRNA methylphosphate capping enzyme

1

10

High-throughput

0.437

High

821678

FBXL6
F-box/LRR-repeat protein 6

1

1

Small-scale

0.437

High

821686

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

7

Small-scale

0.437

High

821656

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

5

High-throughput

0.407

High

821667

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.407

High

821682

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

9

High-throughput

0.407

High

821693

RPH3L
Rab effector Noc2

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024