HitPredict

Interactor 1: Q9VBI1 (Q9VBI1)
DNA replication complex GINS protein SLD5
Gene: Sld5

Interactor 2: PSF2 (Q9VQY9)
Probable DNA replication complex GINS protein PSF2 (GINS complex subunit 2)
Gene: PSF2

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.903

Property	Details
Experiments	16798881, 20709026, 21378962, 14605208
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Sld5~Sld5, SLD5_C~Sld5
Common GO terms	GO:0000727 - double-strand break repair via break-induced replication GO:0000811 - GINS complex GO:0006270 - DNA replication initiation GO:0071162 - CMG complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 228 Dm			1 203
+	Mm
		1307847 SLD5_MOUSE (15-228): 7.59e-79: 237: 37.56		PSF2_MOUSE (1-182): 2.69e-94: 274: 43.96
+	Hs
		1310665 SLD5_HUMAN (15-228): 1.1e-76: 232: 37.56		PSF2_HUMAN (1-182): 1.3e-93: 272: 42.31
+	Ce
		247999 Q9U2W9_CAEEL (22-228): 1.91e-69: 213: 32.87		PSF2_CAEEL (1-160): 2.86e-73: 221: 35.80
+	Sp
		293154 SLD5_SCHPO (24-228): 1.03e-65: 204: 21.50		PSF2_SCHPO (3-180): 1.98e-69: 211: 32.58
+	Sc
		772609 SLD5_YEAST (24-228): 5.76e-64: 202: 20.40		PSF2_YEAST (3-173): 1.15e-48: 159: 27.37
+	Ce
		90265 D9PTP4_CAEEL (156-228): 1.84e-18: 78.2: 27.40		PSF2_CAEEL (1-160): 2.86e-73: 221: 35.80