Protein: EGLN2
Prolyl hydroxylase EGLN2 (EC 1.14.11.-) (Egl nine homolog 2) (EC 1.14.11.29) (Estrogen-induced tag 6) (EIT-6) (HPH-3) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-PH1) (HIF-prolyl hydroxylase 1) (HPH-1) (Prolyl hydroxylase domain-containing protein 1) (PHD1)

Gene: EGLN2
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q96KS0

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0001666 - response to hypoxia
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1085645

HIF1A
Hypoxia-inducible factor 1-alpha

7

14

Small-scale

0.955

High

1296543

EPAS1
Endothelial PAS domain-containing protein 1

2

14

Small-scale

0.785

High

1296545

EGLN3
Prolyl hydroxylase EGLN3

2

4

Small-scale

0.754

High

1296542

EGLN2
Prolyl hydroxylase EGLN2

1

4

Small-scale

0.618

High

199137

SIAH2
E3 ubiquitin-protein ligase SIAH2

2

3

Small-scale

0.584

High

1296546

Q9HCK3
KIAA1569 protein

2

1

Small-scale

0.584

High

942877

SRPK2
SRSF protein kinase 2

1

4

High-throughput

0.569

High

625561

CDK2
Cyclin-dependent kinase 2

1

4

Small-scale

0.561

High

579281

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

2

Small-scale

0.552

High

542758

ETS2
Protein C-ets-2

1

1

High-throughput

0.541

High

1296551

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

5

High-throughput

0.536

High

214348

SPOP
Speckle-type POZ protein

1

3

Small-scale

0.501

High

566451

KPCA
Protein kinase C alpha type

1

2

Small-scale

0.501

High

1294567

TET5A
Terminal nucleotidyltransferase 5A

1

1

High-throughput

0.481

High

63208

WTIP
Wilms tumor protein 1-interacting protein

1

10

Small-scale

0.479

High

208178

SPY2
Protein sprouty homolog 2

1

2

Small-scale

0.479

High

244799

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

515488

CDK4
Cyclin-dependent kinase 4

1

6

Small-scale

0.479

High

625000

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

3

Small-scale

0.479

High

649144

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

14

Small-scale

0.479

High

796334

MAGAB
Melanoma-associated antigen 11

1

6

Small-scale

0.479

High

960229

CDK6
Cyclin-dependent kinase 6

1

6

Small-scale

0.479

High

1042300

CUL3
Cullin-3

1

1

Small-scale

0.479

High

1044056

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

Small-scale

0.479

High

1045135

RUNX3
Runt-related transcription factor 3

1

1

Small-scale

0.479

High

1076507

TRIP6
Thyroid receptor-interacting protein 6

1

10

Small-scale

0.479

High

1274166

LPP
Lipoma-preferred partner

1

10

Small-scale

0.479

High

1281315

FBXW7
F-box/WD repeat-containing protein 7

1

1

Small-scale

0.479

High

1294442

AJUBA
LIM domain-containing protein ajuba

1

11

Small-scale

0.479

High

1296547

LIMD1
LIM domain-containing protein 1

1

11

Small-scale

0.479

High

1296548

PRP19
Pre-mRNA-processing factor 19

1

3

Small-scale

0.479

High

1296550

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

1

6

Small-scale

0.479

High

1033134

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

0

Small-scale

0.458

High

517409

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.457

High

1296549

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.438

High

1136784

Q5TF85
polynucleotide adenylyltransferase

1

1

High-throughput

0.417

High

1296544

C1QT2
Complement C1q tumor necrosis factor-related protein 2

1

0

High-throughput

0.279

Low

344548

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024