HitPredict

Interactor 1: Q9VGF9 (Q9VGF9)
Aurora kinase (EC 2.7.11.1)
Gene: aurA

Interactor 2: Q9VI72 (Q9VI72)
Spindle assembly abnormal 4
Gene: Sas-4

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	27558293
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0007098 - centrosome cycle GO:0051299 - centrosome separation
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 411 Dm			1 901
+	Hs
		681696 AKT1_HUMAN (118-408): 2.05e-130: 385: 30.77		MYH9_HUMAN (377-795): 4.65e-17: 88.7: 8.14
+	Hs
		528433 AURKC_HUMAN (115-411): 1.91e-130: 379: 55.33		MYH8_HUMAN (204-842): 4.52e-17: 88.7: 11.27
+	Hs
		568567 KAPCA_HUMAN (143-406): 4.78e-130: 379: 31.23		MYH9_HUMAN (377-795): 4.65e-17: 88.7: 8.14
+	Hs
		551616 AKT1_HUMAN (118-408): 2.05e-130: 385: 30.77		DESP_HUMAN (263-659): 1.22e-14: 81.1: 11.33
+	Hs
		528359 KAPCB_HUMAN (143-406): 3.24e-130: 380: 31.23		MYH6_HUMAN (242-708): 2.42e-14: 79.9: 8.96
+	Hs
		522653 AURKC_HUMAN (115-411): 1.91e-130: 379: 55.33		MYH7_HUMAN (242-698): 2.02e-14: 80.3: 9.37
+	Hs
		568568 KAPCA_HUMAN (143-406): 4.78e-130: 379: 31.23		MYH10_HUMAN (204-665): 2.38e-13: 76.8: 11.61
+	Hs
		522538 KAPCB_HUMAN (143-406): 3.24e-130: 380: 31.23		MYH1_HUMAN (216-628): 3.66e-12: 72.9: 10.15
+	Hs
		610795 KAPCB_HUMAN (143-406): 3.24e-130: 380: 31.23		MYH2_HUMAN (407-821): 4.49e-12: 72.6: 8.75
+	Hs
		522582 AURKC_HUMAN (115-411): 1.91e-130: 379: 55.33		MYH1_HUMAN (216-628): 3.66e-12: 72.9: 10.15
+	Hs
		610802 KAPCB_HUMAN (143-406): 3.24e-130: 380: 31.23		MYH4_HUMAN (216-607): 1.43e-10: 67.5: 10.27
+	Hs
		1357872 AURKC_HUMAN (115-411): 1.91e-130: 379: 55.33		MYH4_HUMAN (216-607): 1.43e-10: 67.5: 10.27
+	Hs
		728527 AURKC_HUMAN (115-411): 1.91e-130: 379: 55.33		MYH11_HUMAN (440-877): 5.1e-09: 62.5: 10.46
+	Hs
		1189785 AURKB_HUMAN (97-411): 7.5e-106: 318: 53.46		MYH14_HUMAN (399-691): 2.48e-23: 109: 16.17
+	Hs
		724962 AURKB_HUMAN (97-411): 7.5e-106: 318: 53.46		MYH9_HUMAN (377-795): 4.65e-17: 88.7: 8.14
+	Hs
		551805 AURKB_HUMAN (97-411): 7.5e-106: 318: 53.46		DESP_HUMAN (263-659): 1.22e-14: 81.1: 11.33
+	Hs
		725220 AURKB_HUMAN (97-411): 7.5e-106: 318: 53.46		MYH10_HUMAN (204-665): 2.38e-13: 76.8: 11.61
+	Hs
		1068636 AURKB_HUMAN (97-411): 7.5e-106: 318: 53.46		PLEC_HUMAN (226-645): 8.99e-10: 65.2: 8.26
+	Hs
		728503 AURKB_HUMAN (97-411): 7.5e-106: 318: 53.46		MYH11_HUMAN (440-877): 5.1e-09: 62.5: 10.46