HitPredict

Interactor 1: GPI8 (Q92643)
GPI-anchor transamidase (EC 2.6.1.-) (GPI-anchor transamidase component PIGK, catalytic subunit) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K)
Gene: PIGK

Interactor 2: PIGS (Q96S52)
GPI-anchor transamidase component PIGS (Phosphatidylinositol-glycan biosynthesis class S protein)
Gene: PIGS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.881

The method score is based on:

Property Details
Experiments 26496610, 26186194, 11483512, 12802054
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PIG-S~Peptidase_C13
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0016020 - membrane
GO:0016255 - attachment of GPI anchor to protein
GO:0042765 - GPI-anchor transamidase complex
and 1 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 395
Hs

1 555
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025