Protein: RPOA
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)

Gene: RPOA
Organism: Escherichia coli K-12
Interactions: 100
UniProt ID: P0A7Z4

Gene Ontology (top 5):
GO:0000345 - cytosolic DNA-directed RNA polymerase complex
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

462640

RPOC
DNA-directed RNA polymerase subunit beta'

5

4

Small-scale

0.926

High

462673

RPOH
RNA polymerase sigma factor RpoH

3

4

High-throughput

0.848

High

340856

RPOD
RNA polymerase sigma factor RpoD

2

4

High-throughput

0.789

High

462641

RPOB
DNA-directed RNA polymerase subunit beta

2

4

High-throughput

0.789

High

462680

RP54
RNA polymerase sigma-54 factor

2

1

High-throughput

0.789

High

462664

NUSA
Transcription termination/antitermination protein NusA

2

0

Small-scale

0.765

High

462665

NUSG
Transcription termination/antitermination protein NusG

2

0

High-throughput

0.749

High

462692

RAPA
RNA polymerase-associated protein RapA

2

0

High-throughput

0.749

High

461245

RS10
Small ribosomal subunit protein uS10

2

0

High-throughput

0.736

High

462695

RL24
Large ribosomal subunit protein uL24

2

0

High-throughput

0.736

High

462668

RHO
Transcription termination factor Rho

2

0

High-throughput

0.720

High

462663

FLIA
RNA polymerase sigma factor FliA

1

4

High-throughput

0.691

High

462693

RL2
Large ribosomal subunit protein uL2

3

0

Small-scale

0.635

High

462676

RPOS
RNA polymerase sigma factor RpoS

1

4

High-throughput

0.625

High

462657

ROB
Right origin-binding protein

1

0

High-throughput

0.613

High

458850

GREA
Transcription elongation factor GreA

2

1

High-throughput

0.612

High

462275

RS5
Small ribosomal subunit protein uS5

2

1

High-throughput

0.612

High

462648

CSPC
Cold shock-like protein CspC

2

1

High-throughput

0.601

High

462636

RPOZ
DNA-directed RNA polymerase subunit omega

1

0

High-throughput

0.593

High

462635

RPOA
DNA-directed RNA polymerase subunit alpha

1

1

Small-scale

0.590

High

461609

RS19
Small ribosomal subunit protein uS19

2

1

High-throughput

0.588

High

462656

DBHB
DNA-binding protein HU-beta

2

1

High-throughput

0.588

High

462661

RS15
Small ribosomal subunit protein uS15

2

1

High-throughput

0.588

High

462672

RS1
Small ribosomal subunit protein bS1

2

1

High-throughput

0.588

High

462684

LHR
Probable ATP-dependent helicase Lhr

1

0

High-throughput

0.586

High

358362

RL15
Large ribosomal subunit protein uL15

2

0

High-throughput

0.585

High

462077

RS4
Small ribosomal subunit protein uS4

2

0

High-throughput

0.585

High

356926

RS6
Small ribosomal subunit protein bS6

2

0

High-throughput

0.576

High

460618

RL19
Large ribosomal subunit protein bL19

2

0

High-throughput

0.576

High

460937

RL28
Large ribosomal subunit protein bL28

2

0

High-throughput

0.576

High

461127

RL33
Large ribosomal subunit protein bL33

2

0

High-throughput

0.576

High

461643

RS20
Small ribosomal subunit protein bS20

2

0

High-throughput

0.576

High

462669

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.576

High

462671

RS14
Small ribosomal subunit protein uS14

2

0

High-throughput

0.576

High

462698

RS21
Small ribosomal subunit protein bS21

2

0

High-throughput

0.576

High

460908

RL27
Large ribosomal subunit protein bL27

2

0

High-throughput

0.563

High

462637

TPIS
Triosephosphate isomerase

2

0

High-throughput

0.563

High

462644

G3P1
Glyceraldehyde-3-phosphate dehydrogenase A

2

0

High-throughput

0.563

High

462646

MREB
Cell shape-determining protein MreB

2

0

High-throughput

0.563

High

462651

YBCJ
Putative RNA-binding protein YbcJ

2

0

High-throughput

0.563

High

462659

RL16
Large ribosomal subunit protein uL16

2

0

High-throughput

0.563

High

462660

RL23
Large ribosomal subunit protein uL23

2

0

High-throughput

0.563

High

462677

SYD
Aspartate--tRNA ligase

2

0

High-throughput

0.563

High

462679

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase

2

0

High-throughput

0.563

High

462699

NFI
Endonuclease V

2

0

High-throughput

0.563

High

462674

SSB
Single-stranded DNA-binding protein

2

0

High-throughput

0.547

High

462643

FUR
Ferric uptake regulation protein

1

0

High-throughput

0.513

High

462645

PTA
Phosphate acetyltransferase

1

0

High-throughput

0.513

High

462652

COABC
Coenzyme A biosynthesis bifunctional protein CoaBC

1

0

High-throughput

0.513

High

462653

EBGC
Evolved beta-galactosidase subunit beta

1

0

High-throughput

0.513

High

462670

RL6
Large ribosomal subunit protein uL6

1

0

High-throughput

0.513

High

462678

FECI
Ferric citrate uptake sigma factor FecI

1

0

High-throughput

0.513

High

462687

YEGD
Uncharacterized chaperone protein YegD

1

0

High-throughput

0.513

High

462689

ETK
Tyrosine-protein kinase etk

1

0

High-throughput

0.513

High

357021

RS7
Small ribosomal subunit protein uS7

1

1

High-throughput

0.484

High

393730

PNP
Polyribonucleotide nucleotidyltransferase

1

1

High-throughput

0.484

High

460730

RL1
Large ribosomal subunit protein uL1

1

1

High-throughput

0.484

High

461729

RS2
Small ribosomal subunit protein uS2

1

1

High-throughput

0.484

High

461892

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.484

High

462647

CSPA
Cold shock protein CspA

1

1

High-throughput

0.484

High

462655

DBHA
DNA-binding protein HU-alpha

1

1

High-throughput

0.484

High

462685

GREB
Transcription elongation factor GreB

1

1

High-throughput

0.484

High

462694

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.484

High

340908

DPO1
DNA polymerase I

1

0

High-throughput

0.464

High

409407

TSAD
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.464

High

415745

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.464

High

420911

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

1

0

High-throughput

0.464

High

421179

RF2
Peptide chain release factor RF2

1

0

High-throughput

0.464

High

439425

USG
USG-1 protein

1

0

High-throughput

0.464

High

458910

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

460507

RL7
Large ribosomal subunit protein bL12

1

0

High-throughput

0.464

High

461400

RS13
Small ribosomal subunit protein uS13

1

0

High-throughput

0.464

High

461509

RS16
Small ribosomal subunit protein bS16

1

0

High-throughput

0.464

High

462649

RL13
Large ribosomal subunit protein uL13

1

0

High-throughput

0.464

High

462654

SSPA
Stringent starvation protein A

1

0

High-throughput

0.464

High

462666

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.464

High

462675

RCSB
Transcriptional regulatory protein RcsB

1

0

High-throughput

0.464

High

462682

WAAU
Putative lipopolysaccharide heptosyltransferase 4

1

0

High-throughput

0.464

High

462691

OBG
GTPase ObgE/CgtA

1

0

High-throughput

0.464

High

462696

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.464

High

462697

RL5
Large ribosomal subunit protein uL5

1

0

High-throughput

0.464

High

459894

NAGB
Glucosamine-6-phosphate deaminase

1

0

High-throughput

0.458

High

462639

YEEX
UPF0265 protein YeeX

1

0

High-throughput

0.458

High

462642

RIMI
[Ribosomal protein bS18]-alanine N-acetyltransferase

1

0

High-throughput

0.458

High

462658

YIFE
UPF0438 protein YifE

1

0

High-throughput

0.458

High

462681

YIDC
Membrane protein insertase YidC

1

0

Small-scale

0.458

High

462686

POTF
Putrescine-binding periplasmic protein PotF

1

0

High-throughput

0.458

High

462700

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

462701

KDGR
HTH-type transcriptional regulator KdgR

1

0

High-throughput

0.458

High

462702

MSRC
Free methionine-R-sulfoxide reductase

1

0

High-throughput

0.458

High

462703

YQHD
Alcohol dehydrogenase YqhD

1

0

High-throughput

0.458

High

462683

WECG
UDP-N-acetyl-D-mannosaminuronic acid transferase

2

0

High-throughput

0.313

High

462650

HYBE
Hydrogenase-2 operon protein HybE

1

0

High-throughput

0.279

Low

462667

YBBO
Uncharacterized oxidoreductase YbbO

1

0

High-throughput

0.261

Low

462638

YACL
UPF0231 protein YacL

1

0

High-throughput

0.253

Low

462662

CEDA
Cell division activator CedA

1

0

High-throughput

0.253

Low

462704

YGCP
Uncharacterized protein YgcP

1

0

High-throughput

0.253

Low

462688

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

462690

AG43
Antigen 43

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024