HitPredict

Interactor 1: GPI8 (Q92643)
GPI-anchor transamidase (EC 2.6.1.-) (GPI-anchor transamidase component PIGK, catalytic subunit) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K)
Gene: PIGK

Interactor 2: PIGU (Q9H490)
GPI-anchor transamidase component PIGU (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U) (Phosphatidylinositol glycan anchor biosynthesis class U protein)
Gene: PIGU

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.691

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 12802054
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003923 - GPI-anchor transamidase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0016020 - membrane
GO:0016255 - attachment of GPI anchor to protein
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 395
Hs

1 435
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025