Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Interactor 2: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 29568061, 31843895, 11835406, 21985244, 23602568, 11440715, 25860027, 24879152, 19303846, 24165324
Identification Methods affinity chromatography technology, proximity labelling technology, enzymatic study, x-ray crystallography, protein kinase assay
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0001837 - epithelial to mesenchymal transition
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0002020 - protease binding
GO:0002039 - p53 binding
GO:0003170 - heart valve development
and 99 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 420
Hs

1 420
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Last updated: 15 Jul 2024