HitPredict

Interactor 1: Q9VHB5 (Q9VHB5)
SD10846p (Vacuolar protein sorting 45)
Gene: Vps45

Interactor 2: Q9VR90 (Q9VR90)
Syntaxin 16
Gene: Syx16

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.837

Property	Details
Experiments	18685079, 14605208, 15710747
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	SNARE~Sec1
Common GO terms	GO:0000139 - Golgi membrane GO:0000149 - SNARE binding GO:0006886 - intracellular protein transport GO:0007269 - neurotransmitter secretion GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 574 Dm			1 352
+	Dm
		1325739 Q9VHB5_DROME (1-574): 0: 627: 100.00		Q9GU66_DROME (212-343): 1.66e-33: 122: 100.00
+	Hs
		152179 VPS45_HUMAN (1-564): 0: 528: 53.51		STX16_HUMAN (1-330): 1.04e-57: 191: 34.38
+	Dm
		1178789 Q9VHB5_DROME (1-574): 0: 627: 100.00		Q7K0X9_DROME (103-350): 2.06e-20: 91.5: 21.43
+	Mm
		192851 STXB2_MOUSE (22-558): 2.17e-176: 513: 19.79		STX1A_MOUSE (27-352): 7.25e-57: 188: 16.56
+	Dm
		1367130 Q9VHB5_DROME (1-574): 0: 627: 100.00		Q9VU45_DROME (216-352): 3.98e-14: 73.8: 25.00
+	Rn
		699178 STXB2_RAT (2-558): 9.39e-175: 509: 19.43		STX1A_RAT (27-352): 9.27e-57: 188: 16.56
+	At
		221473 VPS45_ARATH (1-553): 4.8e-172: 501: 41.27		SYP41_ARATH (1-352): 1.09e-58: 194: 25.00
+	Hs
		1017818 VPS45_HUMAN (1-564): 0: 528: 53.51		STX4_HUMAN (13-350): 4.35e-48: 165: 14.75
+	Hs
		699262 STXB2_HUMAN (22-558): 2.5e-173: 505: 19.79		STX2_HUMAN (41-350): 1.03e-56: 188: 14.52
+	At
		221477 VPS45_ARATH (1-553): 4.8e-172: 501: 41.27		SYP42_ARATH (1-352): 7.68e-57: 189: 23.85
+	At
		221476 VPS45_ARATH (1-553): 4.8e-172: 501: 41.27		SYP43_ARATH (1-352): 2.66e-56: 188: 23.95
+	Hs
		178807 VPS45_HUMAN (1-564): 0: 528: 53.51		STX7_HUMAN (94-352): 1.3e-45: 158: 21.46
+	Rn
		838510 STXB2_RAT (2-558): 9.39e-175: 509: 19.43		STX2_RAT (27-332): 1.11e-51: 175: 13.07
+	Hs
		898829 STXB1_HUMAN (22-555): 1.86e-169: 495: 18.50		STX1B_HUMAN (27-351): 2.88e-57: 189: 16.31
+	Hs
		1205380 VPS45_HUMAN (1-564): 0: 528: 53.51		STX12_HUMAN (89-337): 3.66e-44: 155: 20.16
+	Hs
		699253 STXB1_HUMAN (22-555): 1.86e-169: 495: 18.50		STX2_HUMAN (41-350): 1.03e-56: 188: 14.52
+	Bt
		699167 STXB1_BOVIN (22-555): 1.86e-169: 495: 18.50		STX1A_BOVIN (27-352): 1.65e-56: 187: 16.87
+	Mm
		936823 STXB2_MOUSE (22-558): 2.17e-176: 513: 19.79		STX4_MOUSE (13-350): 5.2e-47: 163: 14.45
+	Hs
		901778 STXB1_HUMAN (22-555): 1.86e-169: 495: 18.50		STX5_HUMAN (1-333): 1.69e-49: 171: 16.47
+	Hs
		901776 STXB1_HUMAN (22-555): 1.86e-169: 495: 18.50		STX4_HUMAN (13-350): 4.35e-48: 165: 14.75