HitPredict

Interactor 1: JHD1 (Q9VHH9)
JmjC domain-containing histone demethylation protein 1 (EC 1.14.11.27) (Lysine (K)-specific demethylase 2) ([Histone-H3]-lysine-36 demethylase 1)
Gene: Kdm2

Interactor 2: Q9VV77 (Q9VV77)
Lethal (3) 73Ah, isoform A (Lethal (3) 73Ah, isoform B) (RE11339p)
Gene: l(3)73Ah

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	36070387
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1345 Dm			1 222
+	Dm
		728809 JHD1_DROME (1-1345): 0: 1477: 100.00		PSC_DROME (2-218): 1.16e-48: 172: 34.69
+	Dm
		627171 JHD1_DROME (1-1345): 0: 1477: 100.00		SUZ2_DROME (7-218): 1.08e-42: 155: 24.55
+	Dm
		1361711 JHD1_DROME (1-1345): 0: 1477: 100.00		RING1_DROME (2-124): 8.01e-29: 113: 21.77
+	Hs
		1108521 KDM2B_HUMAN (42-1322): 0: 1133: 29.87		PCGF3_HUMAN (1-222): 1.25e-61: 194: 54.55
+	Hs
		718034 KDM2B_HUMAN (42-1322): 0: 1133: 29.87		BMI1_HUMAN (2-219): 9.77e-59: 189: 36.91
+	Hs
		718413 KDM2B_HUMAN (42-1322): 0: 1133: 29.87		PCGF2_HUMAN (2-219): 1.09e-55: 182: 35.17
+	Hs
		1245590 KDM2B_HUMAN (42-1322): 0: 1133: 29.87		PCGF1_HUMAN (2-219): 3.55e-53: 173: 39.82
+	Mm
		639474 KDM2B_MOUSE (35-1322): 0: 1106: 29.93		BMI1_MOUSE (2-219): 2.13e-58: 188: 37.23
+	Hs
		1197574 KDM2B_HUMAN (42-1322): 0: 1133: 29.87		PCGF5_HUMAN (2-222): 1.99e-47: 158: 37.01
+	Hs
		1245594 KDM2B_HUMAN (42-1322): 0: 1133: 29.87		PCGF6_HUMAN (2-216): 2.25e-44: 153: 38.12
+	Mm
		1158236 KDM2B_MOUSE (35-1322): 0: 1106: 29.93		PCGF1_MOUSE (2-219): 4.7e-53: 172: 39.38
+	Hs
		1245587 KDM2B_HUMAN (42-1322): 0: 1133: 29.87		RING2_HUMAN (1-124): 1.78e-31: 119: 21.60
+	Hs
		987996 KDM2B_HUMAN (42-1322): 0: 1133: 29.87		RING1_HUMAN (2-124): 2.4e-29: 114: 22.58
+	Mm
		1158239 KDM2B_MOUSE (35-1322): 0: 1106: 29.93		RING2_MOUSE (1-124): 1.56e-31: 119: 21.60
+	Mm
		193408 KDM2B_MOUSE (35-1322): 0: 1106: 29.93		RING1_MOUSE (2-124): 3.14e-30: 117: 22.58
+	Hs
		1311563 KDM2A_HUMAN (32-1329): 0: 935: 30.59		PCGF1_HUMAN (2-219): 3.55e-53: 173: 39.82
+	Hs
		718320 PHF8_HUMAN (34-546): 0: 651: 33.78		BMI1_HUMAN (2-219): 9.77e-59: 189: 36.91
+	Hs
		1019385 PHF8_HUMAN (34-546): 0: 651: 33.78		TRI26_HUMAN (1-199): 3.83e-30: 118: 15.00
+	Hs
		536886 FXL19_HUMAN (688-1317): 4.6e-147: 464: 25.85		TRI27_HUMAN (1-200): 1.75e-30: 119: 16.74
+	Hs
		718044 FBX41_HUMAN (880-1322): 4.63e-59: 222: 18.91		BMI1_HUMAN (2-219): 9.77e-59: 189: 36.91