Protein: STRAP
Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD)

Gene: STRAP
Organism: Homo sapiens
Interactions: 217
UniProt ID: Q9Y3F4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0000387 - spliceosomal snRNP assembly
GO:0003723 - RNA binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1256695

GEMI5
Gem-associated protein 5

3

18

High-throughput

0.871

High

1377696

STRAP
Serine-threonine kinase receptor-associated protein

2

17

Small-scale

0.776

High

1084945

SMN
Survival motor neuron protein

8

1

Small-scale

0.754

High

1355473

DDX20
Probable ATP-dependent RNA helicase DDX20

5

17

High-throughput

0.718

High

1263377

GEMI6
Gem-associated protein 6

6

0

Small-scale

0.703

High

1333352

GEMI7
Gem-associated protein 7

6

0

Small-scale

0.703

High

269091

CSDE1
Cold shock domain-containing protein E1

6

0

High-throughput

0.702

High

1310578

LARP6
La-related protein 6

3

8

High-throughput

0.667

High

157787

GEMI2
Gem-associated protein 2

4

0

Small-scale

0.664

High

884113

GEMI4
Gem-associated protein 4

4

0

High-throughput

0.664

High

1347580

GEMI8
Gem-associated protein 8

4

0

High-throughput

0.664

High

912598

SMD2
Small nuclear ribonucleoprotein Sm D2

3

4

Small-scale

0.660

High

442624

RU17
U1 small nuclear ribonucleoprotein 70 kDa

3

10

High-throughput

0.656

High

738595

TGFR1
TGF-beta receptor type-1

3

2

Small-scale

0.640

High

999242

EP300
Histone acetyltransferase p300

3

15

Small-scale

0.640

High

146885

CDKA1
Cyclin-dependent kinase 2-associated protein 1

2

2

High-throughput

0.628

High

513650

PYC
Pyruvate carboxylase, mitochondrial

2

13

High-throughput

0.628

High

1075593

TSN
Translin

2

2

High-throughput

0.628

High

1304884

TSNAX
Translin-associated protein X

2

2

High-throughput

0.628

High

1343470

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

3

High-throughput

0.628

High

1350262

ZNFX1
NFX1-type zinc finger-containing protein 1

2

9

High-throughput

0.628

High

792118

HD
Huntingtin

2

2

High-throughput

0.621

High

539200

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

7

Small-scale

0.619

High

815309

TISD
mRNA decay activator protein ZFP36L2

1

1

High-throughput

0.618

High

828066

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

5

High-throughput

0.618

High

896272

UBC12
NEDD8-conjugating enzyme Ubc12

1

6

High-throughput

0.618

High

909379

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

10

High-throughput

0.618

High

1064885

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

8

High-throughput

0.618

High

1080510

EZH2
Histone-lysine N-methyltransferase EZH2

1

17

High-throughput

0.618

High

1172393

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.618

High

1173974

RAPH1
Ras-associated and pleckstrin homology domains-containing protein 1

1

7

High-throughput

0.618

High

1200778

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.618

High

1326058

ARP6
Actin-related protein 6

1

7

High-throughput

0.618

High

1331701

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.618

High

1343837

ANLN
Anillin

1

6

High-throughput

0.618

High

1350139

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

10

High-throughput

0.618

High

1357222

FZR1
Fizzy-related protein homolog

1

19

High-throughput

0.618

High

727110

FUS
RNA-binding protein FUS

2

17

High-throughput

0.611

High

912005

RUXF
Small nuclear ribonucleoprotein F

2

18

High-throughput

0.611

High

1272416

RENT1
Regulator of nonsense transcripts 1

2

5

High-throughput

0.611

High

1330082

CK068
UPF0696 protein C11orf68

2

0

High-throughput

0.602

High

529948

CFTR
Cystic fibrosis transmembrane conductance regulator

2

3

High-throughput

0.601

High

836109

GSK3B
Glycogen synthase kinase-3 beta

2

9

Small-scale

0.601

High

548970

NDKA
Nucleoside diphosphate kinase A

1

1

Small-scale

0.600

High

911776

RUXE
Small nuclear ribonucleoprotein E

2

3

Small-scale

0.595

High

170741

AXIN1
Axin-1

1

0

Small-scale

0.586

High

1174341

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.586

High

167413

SMAD7
Mothers against decapentaplegic homolog 7

2

8

Small-scale

0.584

High

229141

PRKN
E3 ubiquitin-protein ligase parkin

2

20

High-throughput

0.584

High

740093

TGFR2
TGF-beta receptor type-2

2

3

Small-scale

0.584

High

1067664

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.578

High

87597

C9K0J5
Ras association

1

10

High-throughput

0.575

High

1153471

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.575

High

1137977

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

2

10

High-throughput

0.574

High

272777

OFD1
Centriole and centriolar satellite protein OFD1

2

20

High-throughput

0.571

High

375139

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

8

High-throughput

0.571

High

1042903

CUL3
Cullin-3

2

20

High-throughput

0.571

High

1130762

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

11

High-throughput

0.571

High

1272726

CSN5
COP9 signalosome complex subunit 5

2

10

High-throughput

0.571

High

331359

CHK2
Serine/threonine-protein kinase Chk2

1

4

Small-scale

0.569

High

1305606

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

6

Small-scale

0.561

High

231771

KIF1B
Kinesin-like protein KIF1B

1

10

High-throughput

0.553

High

581901

VCAM1
Vascular cell adhesion protein 1

2

5

High-throughput

0.549

High

201836

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

2

High-throughput

0.536

High

387787

P53
Cellular tumor antigen p53

1

6

High-throughput

0.536

High

446851

SNRPA
U1 small nuclear ribonucleoprotein A

1

10

High-throughput

0.536

High

448864

RU1C
U1 small nuclear ribonucleoprotein C

1

4

High-throughput

0.536

High

452927

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.536

High

587082

CSK22
Casein kinase II subunit alpha'

1

11

High-throughput

0.536

High

851753

NEK4
Serine/threonine-protein kinase Nek4

1

9

High-throughput

0.536

High

1182980

SPT6H
Transcription elongation factor SPT6

1

5

High-throughput

0.536

High

1242169

LS14A
Protein LSM14 homolog A

1

7

High-throughput

0.536

High

1251954

RIN3
Ras and Rab interactor 3

1

5

High-throughput

0.536

High

1266443

TCPW
T-complex protein 1 subunit zeta-2

1

20

High-throughput

0.536

High

1268200

LAR4B
La-related protein 4B

1

8

High-throughput

0.536

High

101307

APRIO
Alternative prion protein

2

2

High-throughput

0.533

High

1070703

RNPS1
RNA-binding protein with serine-rich domain 1

1

11

High-throughput

0.515

High

890907

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

4

High-throughput

0.501

High

902817

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.501

High

912760

SMD3
Small nuclear ribonucleoprotein Sm D3

1

20

Small-scale

0.501

High

213411

TLX2
T-cell leukemia homeobox protein 2

1

7

High-throughput

0.500

High

989556

SOX4
Transcription factor SOX-4

1

20

High-throughput

0.500

High

1046682

KLF9
Krueppel-like factor 9

1

19

High-throughput

0.500

High

1305006

KLF6
Krueppel-like factor 6

1

19

High-throughput

0.500

High

1245704

PLBL2
Putative phospholipase B-like 2

1

1

High-throughput

0.489

High

123118

MEN1
Menin

1

5

High-throughput

0.479

High

125811

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

10

Small-scale

0.479

High

134258

DDX3X
ATP-dependent RNA helicase DDX3X

1

12

High-throughput

0.479

High

163507

XPO1
Exportin-1

1

16

High-throughput

0.479

High

182232

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

5

Small-scale

0.479

High

206979

SMAD6
Mothers against decapentaplegic homolog 6

1

8

Small-scale

0.479

High

213678

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

14

High-throughput

0.479

High

233704

NUPR1
Nuclear protein 1

1

4

High-throughput

0.479

High

239635

EIF1B
Eukaryotic translation initiation factor 1b

1

2

High-throughput

0.479

High

260642

TP4A3
Protein tyrosine phosphatase type IVA 3

1

6

High-throughput

0.479

High

282755

RNF8
E3 ubiquitin-protein ligase RNF8

1

10

High-throughput

0.479

High

295445

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.479

High

298920

UFL1
E3 UFM1-protein ligase 1

1

4

High-throughput

0.479

High

323351

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

11

High-throughput

0.479

High

329016

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.479

High

339181

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

348323

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

354618

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

3

High-throughput

0.479

High

370784

ESR1
Estrogen receptor

1

20

High-throughput

0.479

High

380059

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

435193

SP1
Transcription factor Sp1

1

17

Small-scale

0.479

High

453727

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

High-throughput

0.479

High

456025

PARP1
Poly [ADP-ribose] polymerase 1

1

9

High-throughput

0.479

High

554128

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

570216

CEBPB
CCAAT/enhancer-binding protein beta

1

13

High-throughput

0.479

High

591162

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

607746

NDKB
Nucleoside diphosphate kinase B

1

1

High-throughput

0.479

High

652686

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

673116

CCND2
G1/S-specific cyclin-D2

1

11

Small-scale

0.479

High

685129

STIP1
Stress-induced-phosphoprotein 1

1

10

High-throughput

0.479

High

718351

BMI1
Polycomb complex protein BMI-1

1

19

High-throughput

0.479

High

719258

PHB1
Prohibitin 1

1

5

High-throughput

0.479

High

749983

BRCA1
Breast cancer type 1 susceptibility protein

1

9

High-throughput

0.479

High

780370

CCNF
Cyclin-F

1

9

High-throughput

0.479

High

796455

PTN9
Tyrosine-protein phosphatase non-receptor type 9

1

2

High-throughput

0.479

High

809047

YAP1
Transcriptional coactivator YAP1

1

11

High-throughput

0.479

High

813873

CAPZB
F-actin-capping protein subunit beta

1

4

High-throughput

0.479

High

818643

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

842405

PPT1
Palmitoyl-protein thioesterase 1

1

1

High-throughput

0.479

High

843975

FXR1
RNA-binding protein FXR1

1

11

High-throughput

0.479

High

875463

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

893208

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

897867

ABCE1
ATP-binding cassette sub-family E member 1

1

3

High-throughput

0.479

High

943553

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.479

High

950338

SMAD3
Mothers against decapentaplegic homolog 3

1

8

Small-scale

0.479

High

959789

VIGLN
Vigilin

1

17

High-throughput

0.479

High

961335

HSF1
Heat shock factor protein 1

1

4

Small-scale

0.479

High

989208

FMR1
Fragile X messenger ribonucleoprotein 1

1

11

High-throughput

0.479

High

1019187

TP53B
TP53-binding protein 1

1

12

High-throughput

0.479

High

1022246

NFX1
Transcriptional repressor NF-X1

1

13

High-throughput

0.479

High

1023587

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

1

High-throughput

0.479

High

1030570

G3BP1
Ras GTPase-activating protein-binding protein 1

1

8

High-throughput

0.479

High

1036232

BIRC3
Baculoviral IAP repeat-containing protein 3

1

7

High-throughput

0.479

High

1038839

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

1044472

PTC1
Protein patched homolog 1

1

1

Small-scale

0.479

High

1049196

TRI14
Tripartite motif-containing protein 14

1

5

High-throughput

0.479

High

1050309

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

4

High-throughput

0.479

High

1054700

RBM39
RNA-binding protein 39

1

13

High-throughput

0.479

High

1056783

PUM1
Pumilio homolog 1

1

2

High-throughput

0.479

High

1066924

KIF14
Kinesin-like protein KIF14

1

11

High-throughput

0.479

High

1078705

SMAD2
Mothers against decapentaplegic homolog 2

1

8

Small-scale

0.479

High

1148894

VIR
Protein virilizer homolog

1

3

High-throughput

0.479

High

1173292

PAXI1
PAX-interacting protein 1

1

14

High-throughput

0.479

High

1187874

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

9

High-throughput

0.479

High

1192281

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

10

High-throughput

0.479

High

1239776

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

1241083

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1245238

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1256505

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

1266608

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.479

High

1267289

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1272143

CELF1
CUGBP Elav-like family member 1

1

3

High-throughput

0.479

High

1272503

DAZL
Deleted in azoospermia-like

1

6

High-throughput

0.479

High

1272830

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.479

High

1294171

DDRGK
DDRGK domain-containing protein 1

1

6

High-throughput

0.479

High

1302796

RUFY1
RUN and FYVE domain-containing protein 1

1

12

High-throughput

0.479

High

1305990

BARD1
BRCA1-associated RING domain protein 1

1

7

High-throughput

0.479

High

1306753

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.479

High

1310565

RIOK1
Serine/threonine-protein kinase RIO1

1

5

High-throughput

0.479

High

1326799

WWTR1
WW domain-containing transcription regulator protein 1

1

9

High-throughput

0.479

High

1333024

TDRD3
Tudor domain-containing protein 3

1

2

High-throughput

0.479

High

1333830

ECT2
Protein ECT2

1

10

High-throughput

0.479

High

1336065

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

5

High-throughput

0.479

High

1344628

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

1347334

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

1349003

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

2

High-throughput

0.479

High

1349184

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

13

High-throughput

0.479

High

1354174

HDAC6
Histone deacetylase 6

1

20

High-throughput

0.479

High

1354969

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1356423

TNIK
TRAF2 and NCK-interacting protein kinase

1

11

High-throughput

0.479

High

1357252

NOTC3
Neurogenic locus notch homolog protein 3

1

9

Small-scale

0.479

High

1357268

MYO6
Unconventional myosin-VI

1

5

High-throughput

0.479

High

1357901

HDAC5
Histone deacetylase 5

1

20

High-throughput

0.479

High

1377698

TRAF6
TNF receptor-associated factor 6

1

10

High-throughput

0.479

High

1377699

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

18

High-throughput

0.479

High

351778

SOMA
Somatotropin

1

1

High-throughput

0.470

High

670583

PBLD
Phenazine biosynthesis-like domain-containing protein

1

0

Small-scale

0.460

High

245922

HUS1
Checkpoint protein HUS1

1

0

High-throughput

0.458

High

714886

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.458

High

715019

PROF2
Profilin-2

1

0

High-throughput

0.458

High

718540

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

1101392

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1300349

UIF
UAP56-interacting factor

1

0

Small-scale

0.458

High

1327167

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

Small-scale

0.458

High

1329006

MMP28
Matrix metalloproteinase-28

1

0

Small-scale

0.458

High

1377697

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

378223

PRIO
Major prion protein

1

1

High-throughput

0.445

High

402664

JUN
Transcription factor Jun

1

16

High-throughput

0.445

High

497863

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.445

High

891364

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

High-throughput

0.445

High

1037452

TBB3
Tubulin beta-3 chain

1

13

High-throughput

0.445

High

1044302

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

14

High-throughput

0.445

High

1175269

TBA1A
Tubulin alpha-1A chain

1

10

High-throughput

0.445

High

1202209

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

15

High-throughput

0.445

High

1334623

LN28A
Protein lin-28 homolog A

1

8

High-throughput

0.445

High

1349781

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.438

High

206205

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

330032

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

385769

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.437

High

721855

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

1316840

ACE2
Angiotensin-converting enzyme 2

1

2

Small-scale

0.437

High

1348308

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1357021

HECD1
E3 ubiquitin-protein ligase HECTD1

1

18

High-throughput

0.437

High

1377501

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

376350

ANXA1
Annexin A1

1

2

Small-scale

0.408

High

831837

CEBPA
CCAAT/enhancer-binding protein alpha

1

13

High-throughput

0.408

High

1190010

SZRD1
SUZ RNA-binding domain-containing

6

0

High-throughput

0.383

High

1328649

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

225690

PCDH7
Protocadherin-7

1

0

High-throughput

0.249

Low

1169478

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

1309160

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024