HitPredict

Interactor 1: SMD2 (Q9VI10)
Probable small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2)
Gene: SMD2

Interactor 2: Q9W087 (Q9W087)
U6 snRNA-associated Sm-like protein LSm8
Gene: l(3)neo7

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0030532 - small nuclear ribonucleoprotein complex GO:0046540 - U4/U6 x U5 tri-snRNP complex GO:0071011 - precatalytic spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 119 Dm			1 95
+	Dm
		984934 SMD2_DROME (1-119): 2.1e-46: 147: 100.00		RSMB_DROME (3-69): 1.38e-23: 90.7: 32.88
+	Hs
		321387 LSM3_HUMAN (12-111): 9.41e-36: 119: 28.00		LSM8_HUMAN (2-95): 1.25e-33: 113: 69.15
+	Mm
		912214 LSM3_MOUSE (12-111): 9.41e-36: 119: 28.00		LSM8_MOUSE (2-95): 1.25e-33: 113: 69.15
+	Dm
		1367659 SMD2_DROME (1-119): 2.1e-46: 147: 100.00		RUXG_DROME (4-74): 5.83e-21: 80.3: 25.35
+	Hs
		167683 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		LSM1_HUMAN (2-90): 3.41e-25: 93: 26.97
+	Hs
		912425 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		RSMN_HUMAN (2-75): 3.88e-24: 93: 31.33
+	Hs
		538895 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		RSMB_HUMAN (2-75): 1.3e-23: 91.4: 31.33
+	Dm
		1214415 SMD2_DROME (1-119): 2.1e-46: 147: 100.00		Q8IPZ7_DROME (3-83): 1.16e-18: 76: 23.46
+	Hs
		912587 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		LSM7_HUMAN (4-74): 1.57e-23: 87.6: 29.33
+	Hs
		912023 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		RUXG_HUMAN (4-74): 1.42e-21: 81.8: 29.58
+	Hs
		167680 LSM3_HUMAN (12-111): 9.41e-36: 119: 28.00		LSM1_HUMAN (2-90): 3.41e-25: 93: 26.97
+	Mm
		912216 LSM3_MOUSE (12-111): 9.41e-36: 119: 28.00		LSM1_MOUSE (2-90): 3.52e-25: 93: 26.97
+	Hs
		538892 LSM3_HUMAN (12-111): 9.41e-36: 119: 28.00		RSMB_HUMAN (2-75): 1.3e-23: 91.4: 31.33
+	Hs
		68410 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		RUXGL_HUMAN (4-74): 1.04e-19: 77.2: 29.58
+	Hs
		912202 LSM3_HUMAN (12-111): 9.41e-36: 119: 28.00		LSM7_HUMAN (4-74): 1.57e-23: 87.6: 29.33
+	Hs
		912020 LSM3_HUMAN (12-111): 9.41e-36: 119: 28.00		RUXG_HUMAN (4-74): 1.42e-21: 81.8: 29.58
+	Sc
		865981 SMD2_YEAST (3-113): 7.77e-34: 115: 54.05		LSM7_YEAST (4-84): 3.01e-21: 82.2: 23.86
+	Sc
		884829 SMD2_YEAST (3-113): 7.77e-34: 115: 54.05		LSM3_YEAST (4-82): 1.66e-20: 79.5: 23.17
+	Sc
		766960 SMD2_YEAST (3-113): 7.77e-34: 115: 54.05		RSMB_YEAST (2-74): 2.73e-18: 76.8: 29.67
+	Sc
		811667 SMD2_YEAST (3-113): 7.77e-34: 115: 54.05		LSM8_YEAST (2-80): 5.54e-18: 73.7: 32.91