Protein: RRP15
RRP15-like protein (Ribosomal RNA-processing protein 15)

Gene: RRP15
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q9Y3B9

Gene Ontology (top 5):
GO:0000460 - maturation of 5.8S rRNA
GO:0000470 - maturation of LSU-rRNA
GO:0030687 - preribosome, large subunit precursor

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1446795

SSF1
Suppressor of SWI4 1 homolog

2

1

High-throughput

0.811

High

373575

MYC
Myc proto-oncogene protein

3

1

High-throughput

0.585

High

447610

NPM
Nucleophosmin

2

1

High-throughput

0.574

High

1462455

SRPK3
SRSF protein kinase 3

2

2

High-throughput

0.574

High

182395

WDR46
WD repeat-containing protein 46

2

2

High-throughput

0.558

High

522027

H14
Histone H1.4

2

3

High-throughput

0.558

High

1161772

IF16
Gamma-interferon-inducible protein 16

2

1

High-throughput

0.558

High

1017321

H33
Histone H3.3

2

1

High-throughput

0.533

High

397288

ESR1
Estrogen receptor

2

1

High-throughput

0.521

High

976046

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

941309

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.493

High

287203

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

2

High-throughput

0.489

High

288547

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

1

High-throughput

0.489

High

288826

NPM3
Nucleoplasmin-3

1

1

High-throughput

0.489

High

429073

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.489

High

833227

MNDA
Myeloid cell nuclear differentiation antigen

1

1

High-throughput

0.489

High

1006814

SRPK2
SRSF protein kinase 2

1

3

High-throughput

0.489

High

1037453

H11
Histone H1.1

1

3

High-throughput

0.489

High

1061222

SRSF1
Serine/arginine-rich splicing factor 1

1

1

High-throughput

0.489

High

1062160

SRSF4
Serine/arginine-rich splicing factor 4

1

2

High-throughput

0.489

High

1402648

SRPK1
SRSF protein kinase 1

1

2

High-throughput

0.489

High

1490626

DRG1
Developmentally-regulated GTP-binding protein 1

1

1

High-throughput

0.489

High

1032274

EXOSX
Exosome complex component 10

1

0

High-throughput

0.458

High

225146

TLX3
T-cell leukemia homeobox protein 3

1

1

High-throughput

0.437

High

226624

TLX2
T-cell leukemia homeobox protein 2

1

1

High-throughput

0.437

High

406831

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

595653

H15
Histone H1.5

1

3

High-throughput

0.437

High

596438

H12
Histone H1.2

1

3

High-throughput

0.437

High

930092

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

High-throughput

0.437

High

998987

H31
Histone H3.1

1

1

High-throughput

0.437

High

1024953

VIGLN
Vigilin

1

1

High-throughput

0.437

High

1087632

GRSF1
G-rich sequence factor 1

1

1

High-throughput

0.437

High

1194481

LARP7
La-related protein 7

1

2

High-throughput

0.437

High

1339057

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.437

High

1367660

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1418652

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

1

High-throughput

0.437

High

1454374

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.437

High

1461720

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

1491158

MAFB
Transcription factor MafB

1

1

High-throughput

0.437

High

72829

B0UZZ8
WD repeat-containing protein 46

1

2

High-throughput

0.407

High

141179

NOP56
Nucleolar protein 56

2

0

High-throughput

0.318

High

694085

RL10
Large ribosomal subunit protein uL16

2

0

High-throughput

0.318

High

1437426

LN28A
Protein lin-28 homolog A

2

0

High-throughput

0.313

High

979368

RS6
Small ribosomal subunit protein eS6

2

0

High-throughput

0.305

High

1447481

ANLN
Anillin

2

0

High-throughput

0.305

High

1459410

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.305

High

430549

JUN
Transcription factor Jun

2

0

High-throughput

0.298

High

711210

PTN6
Tyrosine-protein phosphatase non-receptor type 6

2

0

High-throughput

0.298

High

191872

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.279

Low

250906

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.279

Low

290802

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.279

Low

624183

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

0

High-throughput

0.279

Low

686541

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.279

Low

785551

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.279

Low

809932

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.279

Low

849273

KSYK
Tyrosine-protein kinase SYK

1

0

High-throughput

0.279

Low

854397

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.279

Low

859516

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.279

Low

860064

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.279

Low

860423

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.279

Low

861030

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.279

Low

898900

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.279

Low

984597

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.279

Low

985966

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.279

Low

998128

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.279

Low

1027872

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.279

Low

1112232

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.279

Low

1114719

CUL3
Cullin-3

1

0

High-throughput

0.279

Low

1127542

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1137205

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

0

High-throughput

0.279

Low

1151241

OASL
2'-5'-oligoadenylate synthase-like protein

1

0

High-throughput

0.279

Low

1152309

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.279

Low

1361804

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.279

Low

1370486

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.279

Low

1389528

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

0

High-throughput

0.279

Low

1395850

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.279

Low

1409881

RBM4B
RNA-binding protein 4B

1

0

High-throughput

0.279

Low

1410787

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.279

Low

1434636

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

1

0

High-throughput

0.279

Low

1451839

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.279

Low

1461418

ZN346
Zinc finger protein 346

1

0

High-throughput

0.279

Low

1491156

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.279

Low

423508

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

1458892

CLN8
Protein CLN8

1

0

Small-scale

0.251

Low

129584

MEN1
Menin

1

0

High-throughput

0.249

Low

158020

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

191174

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.249

Low

194403

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

223440

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.249

Low

272568

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

325185

HEXI1
Protein HEXIM1

1

0

High-throughput

0.249

Low

401743

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.249

Low

463857

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.249

Low

473207

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.249

Low

487908

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.249

Low

558516

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.249

Low

644147

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.249

Low

697304

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.249

Low

786948

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

High-throughput

0.249

Low

810474

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

872920

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

879652

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

898034

CDK9
Cyclin-dependent kinase 9

1

0

High-throughput

0.249

Low

937991

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.249

Low

971335

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

980584

H4
Histone H4

1

0

High-throughput

0.249

Low

981193

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.249

Low

982889

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.249

Low

985086

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.249

Low

995362

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.249

Low

995912

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.249

Low

1033324

EWS
RNA-binding protein EWS

1

0

High-throughput

0.249

Low

1036014

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.249

Low

1058369

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.249

Low

1107361

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

1135193

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

1146887

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.249

Low

1156912

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

1290848

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

1311896

DHX40
Probable ATP-dependent RNA helicase DHX40

1

0

High-throughput

0.249

Low

1313559

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.249

Low

1352855

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

1361265

DNJC9
DnaJ homolog subfamily C member 9

1

0

High-throughput

0.249

Low

1368690

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.249

Low

1384919

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.249

Low

1385930

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.249

Low

1393857

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1411771

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.249

Low

1414630

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.249

Low

1428682

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low

1434302

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1439019

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

High-throughput

0.249

Low

1450953

NLE1
Notchless protein homolog 1

1

0

High-throughput

0.249

Low

1451476

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.249

Low

1491157

KLF12
Krueppel-like factor 12

1

0

High-throughput

0.249

Low

1130546

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025