HitPredict

Interactor 1: Q9VK14 (Q9VK14)
Proteasome subunit alpha type
Gene: Prosalpha6T

Interactor 2: Q9VTQ9 (Q9VTQ9)
AT06668p (Regulatory particle triple-A ATPase 4-related, isoform A) (Regulatory particle triple-A ATPase 4-related, isoform B (EC 5.6.1.5))
Gene: Rpt4R

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome, AAA~Proteasome_A_N, AAA_lid_3~Proteasome_A_N
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 289 Dm			1 398
+	Dm
		820516 Q9VK14_DROME (1-289): 5.25e-128: 367: 100.00		PRS4_DROME (1-389): 2.65e-158: 454: 41.13
+	Dm
		522484 PSA1_DROME (1-237): 1.09e-97: 290: 63.90		PRS4_DROME (1-389): 2.65e-158: 454: 41.13
+	Hs
		637380 PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19		PRS4_HUMAN (4-389): 1.17e-136: 399: 41.71
+	Hs
		637354 PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19		PRS6B_HUMAN (9-390): 1.54e-131: 385: 41.10
+	Hs
		637667 PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41		PRS4_HUMAN (4-389): 1.17e-136: 399: 41.71
+	Hs
		637642 PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41		PRS6B_HUMAN (9-390): 1.54e-131: 385: 41.10
+	Hs
		637341 PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19		PRS7_HUMAN (78-383): 2.64e-102: 311: 48.69
+	Sc
		771348 PSA6_YEAST (1-232): 2.68e-100: 294: 46.58		PRS8_YEAST (22-393): 5.42e-104: 315: 45.16
+	Hs
		637639 PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41		PRS7_HUMAN (78-383): 2.64e-102: 311: 48.69
+	Sc
		703907 PSA6_YEAST (1-232): 2.68e-100: 294: 46.58		PRS7_YEAST (78-395): 1.97e-102: 313: 47.96
+	Dm
		522492 PSA1_DROME (1-237): 1.09e-97: 290: 63.90		Q7KMQ0_DROME (78-383): 1.31e-102: 312: 48.37
+	Hs
		637372 PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19		TERA_HUMAN (123-375): 6.36e-80: 263: 39.13
+	Hs
		637659 PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41		TERA_HUMAN (123-375): 6.36e-80: 263: 39.13
+	Hs
		637383 PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19		PRS10_HUMAN (1-115): 1.73e-12: 70.2: 10.44
+	Hs
		637381 PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19		PRS8_HUMAN (1-107): 2.86e-12: 69.8: 11.22
+	Hs
		637669 PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41		PRS10_HUMAN (1-115): 1.73e-12: 70.2: 10.44
+	Rn
		566253 PSA2_RAT (1-236): 3.55e-101: 297: 29.41		PRS8_RAT (1-107): 2.86e-12: 69.8: 11.22
+	Hs
		637668 PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41		PRS8_HUMAN (1-107): 2.86e-12: 69.8: 11.22
+	Dm
		186097 PSA1_DROME (1-237): 1.09e-97: 290: 63.90		PRS8_DROME (1-107): 6.51e-13: 71.7: 11.22
+	Sc
		771342 PSA6_YEAST (1-232): 2.68e-100: 294: 46.58		PRS10_YEAST (1-103): 2.26e-11: 67.1: 9.71