HitPredict

Interactor 1: LST8 (Q9W328)
Protein LST8 homolog
Gene: LST8

Interactor 2: Q9W437 (Q9W437)
Raptor, isoform B (Raptor, isoform C)
Gene: raptor

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	22068330, 22493059
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0045793 - positive regulation of cell size
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 313 Dm			1 1621
+	Hs
		245633 TBL1X_HUMAN (75-312): 2.21e-60: 203: 15.54		TBL1R_HUMAN (1138-1479): 4.39e-51: 191: 8.43
+	Hs
		903551 NLE1_HUMAN (156-311): 1.06e-46: 165: 22.22		WDR5_HUMAN (1394-1620): 7.76e-60: 211: 11.40
+	Hs
		196984 PRP4_HUMAN (109-310): 1.97e-43: 157: 22.38		WDR5_HUMAN (1394-1620): 7.76e-60: 211: 11.40
+	Hs
		792949 LIS1_HUMAN (161-310): 4.35e-41: 148: 18.00		WDR5_HUMAN (1394-1620): 7.76e-60: 211: 11.40
+	Mm
		925836 LIS1_MOUSE (161-310): 3.21e-41: 149: 18.00		LIS1_MOUSE (1396-1621): 3.03e-55: 200: 10.12
+	Hs
		792935 LIS1_HUMAN (161-310): 4.35e-41: 148: 18.00		LIS1_HUMAN (1396-1621): 3.21e-55: 200: 10.12
+	Dm
		1358845 WDS_DROME (3-154): 8.57e-36: 133: 17.72		WDS_DROME (1394-1620): 8.88e-59: 209: 11.84
+	Hs
		903349 WDR5B_HUMAN (3-150): 1.68e-34: 129: 19.48		WDR5_HUMAN (1394-1620): 7.76e-60: 211: 11.40
+	Sc
		630844 NLE1_YEAST (183-308): 1.04e-28: 117: 26.56		NLE1_YEAST (1338-1620): 3.53e-60: 218: 8.87
+	Hs
		903428 SNR40_HUMAN (199-304): 1.29e-24: 103: 22.43		WDR5_HUMAN (1394-1620): 7.76e-60: 211: 11.40
+	Hs
		1309163 TBL1Y_HUMAN (156-311): 8.94e-30: 120: 15.95		TBL1R_HUMAN (1138-1479): 4.39e-51: 191: 8.43
+	Hs
		903482 LST8_HUMAN (3-132): 1.83e-15: 77.3: 16.67		WDR5_HUMAN (1394-1620): 7.76e-60: 211: 11.40
+	Hs
		1346954 NLE1_HUMAN (156-311): 1.06e-46: 165: 22.22		NLE1_HUMAN (840-1339): 1.63e-22: 105: 9.96
+	Sc
		756514 LST8_YEAST (4-223): 1.67e-38: 139: 16.74		KOG1_YEAST (1327-1619): 8.5e-30: 131: 17.12
+	Hs
		921751 NLE1_HUMAN (156-311): 1.06e-46: 165: 22.22		GBB2_HUMAN (1464-1620): 2e-21: 99.5: 20.89
+	Hs
		793026 LIS1_HUMAN (161-310): 4.35e-41: 148: 18.00		KTNB1_HUMAN (1445-1620): 5.14e-24: 111: 19.77
+	Hs
		197071 PRP4_HUMAN (109-310): 1.97e-43: 157: 22.38		SNR40_HUMAN (1525-1620): 2.2e-17: 87.9: 16.50
+	At
		1339921 LST81_ARATH (3-174): 1.03e-34: 129: 14.05		RTOR2_ARATH (1364-1618): 1.34e-17: 91.8: 11.31
+	At
		1275315 LST81_ARATH (3-174): 1.03e-34: 129: 14.05		RTOR1_ARATH (1432-1619): 1.02e-13: 79.1: 13.50
+	Hs
		1288388 SNR40_HUMAN (199-304): 1.29e-24: 103: 22.43		PRP19_HUMAN (1429-1615): 3.76e-10: 66.4: 16.49