HitPredict

Interactor 1: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Interactor 2: NOP58 (Q9Y2X3)
Nucleolar protein 58 (Nucleolar protein 5)
Gene: NOP58

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	35271311, 28561026, 33961781, 17643375, 17636026
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001094 - TFIID-class transcription factor complex binding GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0051117 - ATPase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 463 Hs			1 529
+	Hs
		1377041 RUVB1_HUMAN (8-451): 0: 655: 42.67		NOP58_HUMAN (1-529): 0: 602: 100.00
+	Mm
		888072 RUVB1_MOUSE (8-451): 0: 656: 42.67		NOP58_MOUSE (1-529): 0: 594: 93.10
+	Sc
		1015639 RUVB2_YEAST (7-451): 0: 650: 68.76		NOP58_YEAST (2-438): 2.75e-164: 477: 49.55
+	Sc
		978061 RUVB1_YEAST (12-451): 0: 605: 41.72		NOP58_YEAST (2-438): 2.75e-164: 477: 49.55
+	Hs
		1263057 RUVB1_HUMAN (8-451): 0: 655: 42.67		PRP31_HUMAN (154-528): 1.12e-129: 388: 21.83
+	Sc
		830836 RUVB2_YEAST (7-451): 0: 650: 68.76		PRP31_YEAST (164-528): 9.61e-71: 236: 20.00
+	Sc
		830824 RUVB1_YEAST (12-451): 0: 605: 41.72		PRP31_YEAST (164-528): 9.61e-71: 236: 20.00