Protein: NUC1
Mitochondrial nuclease (EC 3.1.30.-)

Gene: NUC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 33
UniProt ID: P08466

Gene Ontology (top 5):
GO:0000014 - single-stranded DNA endodeoxyribonuclease activity
GO:0003676 - nucleic acid binding
GO:0004520 - DNA endonuclease activity
GO:0004521 - RNA endonuclease activity
GO:0004529 - DNA exonuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

470204

RNZ
Ribonuclease Z

6

0

Small-scale

0.702

High

470212

YMY9
Glucose-6-phosphate 1-epimerase

4

0

Small-scale

0.657

High

470192

NUC1
Mitochondrial nuclease

1

2

High-throughput

0.618

High

408541

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

Small-scale

0.480

High

380923

H2B1
Histone H2B.1

1

4

Small-scale

0.479

High

381362

H2B2
Histone H2B.2

1

4

Small-scale

0.479

High

470193

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.479

High

470199

ADT2
ADP,ATP carrier protein 2

1

4

Small-scale

0.479

High

470202

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

470207

IMB4
Importin subunit beta-4

1

1

Small-scale

0.479

High

381797

H4
Histone H4

1

0

Small-scale

0.458

High

382789

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

399777

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

416994

VDAC1
Non-selective voltage-gated ion channel 1

1

0

Small-scale

0.458

High

470196

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

470200

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

470201

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

470203

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

470206

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

470208

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

470210

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

470211

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

470213

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

470214

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

470215

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.458

High

470194

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

470198

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.445

High

470209

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

364877

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.249

Low

470205

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

470195

RLA3
Large ribosomal subunit protein P1B

1

0

High-throughput

0.238

Low

470197

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025