HitPredict

Interactor 1: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Interactor 2: TELO2 (Q9Y4R8)
Telomere length regulation protein TEL2 homolog (Protein clk-2 homolog) (hCLK2)
Gene: TELO2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	20801936, 20371770
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016020 - membrane GO:0050821 - protein stabilization
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 456 Hs			1 837
+	Hs
		1376987 RUVB2_HUMAN (2-455): 0: 651: 42.76		TELO2_HUMAN (1-837): 0: 1020: 100.00
+	Sp
		1319466 RUVB1_SCHPO (1-456): 0: 671: 69.96		TEL2_SCHPO (332-837): 3.18e-147: 456: 18.82
+	Sp
		294008 RUVB2_SCHPO (1-455): 0: 639: 42.45		TEL2_SCHPO (332-837): 3.18e-147: 456: 18.82
+	Sc
		858520 RUVB1_YEAST (1-455): 0: 652: 67.39		TEL2_YEAST (510-738): 1.01e-63: 228: 20.25
+	Sc
		858523 RUVB2_YEAST (5-455): 0: 627: 41.72		TEL2_YEAST (510-738): 1.01e-63: 228: 20.25