Protein: DCLK
Serine/threonine-protein kinase zyg-8 (EC 2.7.11.1) (Doublecortin-like and CAM kinase-like protein)

Gene: DCLK, zyg-8
Organism: Caenorhabditis elegans
Interactions: 46
UniProt ID: Q95QC4

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

562928

GLP1
Protein glp-1 [Cleaved into: glp-1/Notch intracellular domain]

2

4

High-throughput

0.743

High

1377052

LIN41
Protein lin-41

2

20

High-throughput

0.576

High

1377055

Q9XUS3
E3 ubiquitin-protein ligase parkin

2

14

High-throughput

0.576

High

1377054

Q9XTZ2
RRM domain-containing protein

1

3

High-throughput

0.555

High

759152

KLE2
Condensin-2 complex subunit kle-2

2

0

High-throughput

0.551

High

1169578

SAS5
Spindle assembly abnormal protein 5

2

0

High-throughput

0.551

High

110828

TACC1
Transforming acid coiled-coil-containing protein 1

1

0

Small-scale

0.545

High

113545

G5EFV4
HMG box domain-containing protein

1

10

High-throughput

0.541

High

836712

14331
14-3-3-like protein 1

1

20

High-throughput

0.541

High

1018508

IFA1
Intermediate filament protein ifa-1

1

16

High-throughput

0.541

High

1166141

Q18605
PHD-type domain-containing protein

1

5

High-throughput

0.541

High

1372589

TCTP
Translationally-controlled tumor protein homolog

1

1

High-throughput

0.541

High

1049134

PSMD3
26S proteasome non-ATPase regulatory subunit 3

2

1

High-throughput

0.526

High

1170230

LMN1
Lamin-1

2

13

High-throughput

0.526

High

1019482

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.518

High

1377018

PAT12
Protein pat-12

1

0

High-throughput

0.518

High

1377050

OAZ
Ornithine decarboxylase antizyme

1

0

High-throughput

0.518

High

1170433

Q21748
BTB domain-containing protein

1

6

High-throughput

0.508

High

305780

FBLN1
Fibulin-1

1

5

High-throughput

0.494

High

420174

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

3

High-throughput

0.494

High

759468

CHTB1
Chitin binding domain

1

7

High-throughput

0.494

High

1068766

Q09983
BPTI/Kunitz inhibitor domain-containing protein

1

19

High-throughput

0.494

High

1170960

Q22631
Apple domain-containing protein

1

5

High-throughput

0.494

High

1377053

ZPT72
Zinc transporter zipt-7.2

1

1

High-throughput

0.494

High

1170733

MIG5
Segment polarity protein dishevelled homolog mig-5

1

20

High-throughput

0.494

High

1377046

Q966C7
Transaldolase

1

1

High-throughput

0.494

High

1377048

Q9GRZ1
Microtubule End Binding Protein

1

8

High-throughput

0.494

High

1346184

Q8T876
Transaldolase

1

1

High-throughput

0.481

High

1170645

Q22095
TNFR-Cys domain-containing protein

1

1

High-throughput

0.464

High

1170427

Q21747
BTB domain-containing protein

1

6

High-throughput

0.457

High

1169968

Q20833
CRAL-TRIO domain-containing protein

1

20

High-throughput

0.451

High

1377049

Q9N5N7
CEntrosomal Protein

1

1

High-throughput

0.451

High

90662

C1P648
CRAL-TRIO domain-containing protein

1

20

High-throughput

0.439

High

116229

H2L2C8
Alpha-actinin, sarcomeric

1

18

High-throughput

0.439

High

1321849

Q8MXV3
CEntrosomal Protein

1

1

High-throughput

0.439

High

1377047

Q9GRZ0
EB1 C-terminal domain-containing protein

1

8

High-throughput

0.439

High

116068

H2L0K1
TNFR-Cys domain-containing protein

1

1

High-throughput

0.417

High

1377056

Q9XVU8
Alpha-actinin, sarcomeric

1

14

High-throughput

0.417

High

1166496

Q19207
3-hydroxy-3-methylglutaryl coenzyme A reductase

2

0

High-throughput

0.300

High

1372656

Q93831
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

2

0

High-throughput

0.300

High

1377051

Q9U211
EB domain-containing protein

2

0

High-throughput

0.300

High

111310

G5ED07
Protein disulfide-isomerase

1

0

High-throughput

0.282

High

115033

H2KY76
THAP-type domain-containing protein

1

0

High-throughput

0.282

High

870585

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.282

High

1019107

P91419
Activated in Blocked Unfolded protein response

1

0

High-throughput

0.282

High

1067164

RIC1
Guanine nucleotide exchange factor subunit R06F6.8

1

0

High-throughput

0.282

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025