Interactor 1: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6
Interactor 2: IRAK3 (Q9Y616)
Interleukin-1 receptor-associated kinase 3 (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) (Inactive IL-1 receptor-associated kinase 3)
Gene: IRAK3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 0.60 | 0.689 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 10383454, 21098228, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, validated two hybrid, two hybrid array, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002755 - MyD88-dependent toll-like receptor signaling pathway GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0051092 - positive regulation of NF-kappaB transcription factor activity and 3 others more... |
| Homologous interactions | 11 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
