Interactor 1: HRS (Q960X8)
Hepatocyte growth factor-regulated tyrosine kinase substrate
Gene: HRS

Interactor 2: Q9W277 (Q9W277)
Vacuolar protein sorting-associated protein 35
Gene: Vps35

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 15710747
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005768 - endosome
GO:0005769 - early endosome
GO:0006897 - endocytosis
GO:0061357 - positive regulation of Wnt protein secretion
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 760
Dm

1 822
+ Hs
+ Hs

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Last updated: 11Aug2025