HitPredict

Interactor 1: PIGT (Q969N2)
GPI-anchor transamidase component PIGT (Phosphatidylinositol-glycan biosynthesis class T protein)
Gene: PIGT

Interactor 2: PIGS (Q96S52)
GPI-anchor transamidase component PIGS (Phosphatidylinositol-glycan biosynthesis class S protein)
Gene: PIGS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.945

The method score is based on:

Property Details
Experiments 28514442, 33961781, 26496610, 11483512, 12802054, unassigned3799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gpi16~PIG-S
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0016020 - membrane
GO:0016255 - attachment of GPI anchor to protein
GO:0042765 - GPI-anchor transamidase complex
and 1 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 578
Hs

1 555
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025