HitPredict

Interactor 1: BIN1 (O08539)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Bridging integrator 1) (SH3 domain-containing protein 9)
Gene: BIN1

Interactor 2: WASL (Q91YD9)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25262827
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0098978 - glutamatergic synapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 588 Mm			1 501
+	Hs
		131177 BIN1_HUMAN (1-587): 1.67e-155: 460: 94.60		SYNJ2_HUMAN (1-474): 5.83e-68: 239: 14.71
+	Mm
		139042 BIN1_MOUSE (1-588): 7.74e-167: 489: 100.00		DYN3_MOUSE (207-351): 2.22e-15: 81.2: 25.16
+	Rn
		139991 BIN1_RAT (1-588): 4.1e-165: 485: 99.15		SYNJ1_RAT (151-497): 5.94e-13: 73.9: 15.41
+	Hs
		126878 BIN1_HUMAN (1-587): 1.67e-155: 460: 94.60		WASL_HUMAN (376-481): 2.65e-18: 89.8: 96.23
+	Dm
		1180683 Q7KLE5_DROME (6-587): 1.54e-75: 253: 25.35		Q9VAT0_DROME (1-500): 7.68e-57: 199: 32.96
+	Mm
		1186718 AMPH_MOUSE (9-588): 1.79e-93: 303: 35.71		DYN3_MOUSE (207-351): 2.22e-15: 81.2: 25.16
+	Rn
		139978 AMPH_RAT (9-547): 1.99e-92: 300: 44.86		SYNJ1_RAT (151-497): 5.94e-13: 73.9: 15.41
+	Hs
		203213 AMPH_HUMAN (84-588): 8.64e-21: 98.7: 18.98		SYNJ1_HUMAN (1-473): 5.48e-78: 268: 15.08
+	Hs
		126939 DNMBP_HUMAN (17-584): 1.07e-76: 267: 14.14		WASL_HUMAN (376-481): 2.65e-18: 89.8: 96.23
+	Hs
		1167839 DNMBP_HUMAN (17-584): 1.07e-76: 267: 14.14		DYN3_HUMAN (207-351): 3.34e-14: 77.3: 23.90
+	Dm
		1361428 DBNL_DROME (126-588): 2.44e-36: 144: 13.22		Q9VAT0_DROME (1-500): 7.68e-57: 199: 32.96
+	Sc
		629680 RV161_YEAST (16-272): 8.38e-62: 206: 19.62		LAS17_YEAST (18-360): 5.29e-31: 128: 21.65
+	Sc
		764174 RV167_YEAST (16-400): 9.74e-59: 205: 14.74		LAS17_YEAST (18-360): 5.29e-31: 128: 21.65
+	Sp
		193724 HOB1_SCHPO (16-358): 3.99e-70: 235: 18.38		WSP1_SCHPO (15-403): 5.14e-20: 95.1: 20.65
+	Hs
		126963 ABI2_HUMAN (280-587): 2.27e-21: 99.8: 14.68		WASL_HUMAN (376-481): 2.65e-18: 89.8: 96.23
+	Hs
		827766 AMPH_HUMAN (84-588): 8.64e-21: 98.7: 18.98		DYN3_HUMAN (207-351): 3.34e-14: 77.3: 23.90
+	Hs
		195960 PLXB1_HUMAN (327-559): 2.46e-14: 78.6: 13.98		PLXB1_HUMAN (293-488): 1.23e-11: 69.7: 16.33
+	Mm
		1351630 PCLO_MOUSE (260-576): 6.89e-10: 64.4: 12.85		PCLO_MOUSE (220-492): 2.97e-14: 78.1: 13.55
+	Dm
		113976 M9PB30_DROME (262-484): 2.53e-10: 65.9: 11.89		M9PB30_DROME (123-361): 9.95e-09: 60.4: 13.20