Protein: UNC89
Muscle M-line assembly protein unc-89 (Inactive serine/threonine-protein kinase unc-89) (Obscurin) (Uncoordinated protein 89)

Gene: UNC89, unc-89
Organism: Caenorhabditis elegans
Interactions: 39
UniProt ID: O01761

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005524 - ATP binding
GO:0008104 - intracellular protein localization
GO:0010628 - positive regulation of gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

145089

RHO1
Ras-like GTP-binding protein rhoA

1

14

Small-scale

0.713

High

145093

VAV
Protein vav-1

1

5

High-throughput

0.656

High

145072

O17566
Protein kinase domain-containing protein

1

3

Small-scale

0.621

High

145077

SULU
Serine/threonine-protein kinase SULU

1

8

Small-scale

0.621

High

145084

KRAF1
Raf homolog serine/threonine-protein kinase

1

2

Small-scale

0.621

High

145091

UNC22
Twitchin

1

19

Small-scale

0.621

High

145092

Q3S1I9
LIM zinc-binding domain-containing protein

2

8

Small-scale

0.619

High

145071

PARV
Paralyzed arrest at two-fold protein 6

1

0

Small-scale

0.589

High

145070

O01960
C2H2-type domain-containing protein

1

1

High-throughput

0.587

High

145075

O44820
Ubiquitin-like domain-containing protein

1

4

High-throughput

0.587

High

145074

O44490
ELKS/RAB6-interacting/CAST family member 2

2

7

High-throughput

0.584

High

111341

G5ED33
Epidermal growth factor receptor pathway substrate 8 splice variant A

1

6

Small-scale

0.555

High

115868

H2L0C1
Fibronectin type-III domain-containing protein

1

13

High-throughput

0.555

High

145088

NHR1
Nuclear hormone receptor family member nhr-1

1

9

Small-scale

0.555

High

110130

G5EBV3
Rac-like GTPase

1

14

Small-scale

0.553

High

145082

RAC1
Ras-related protein ced-10

1

14

Small-scale

0.553

High

145083

CDC42
Cell division control protein 42 homolog

1

17

Small-scale

0.553

High

145095

MEL26
Protein maternal effect lethal 26

1

3

Small-scale

0.549

High

145078

PPM1G
Protein phosphatase ppm-1.G

1

0

High-throughput

0.549

High

145076

MYSP
Paramyosin

1

5

Small-scale

0.527

High

116616

H9G2X3
Serine/threonine protein phosphatase 2A regulatory subunit

1

1

Small-scale

0.523

High

145073

2A51
Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1

1

1

Small-scale

0.523

High

145079

ILB6
Putative insulin-like peptide beta-type 6

1

0

High-throughput

0.494

High

145080

HUM6
Unconventional myosin heavy chain 6

1

4

Small-scale

0.481

High

94740

E0R7K7
K Homology domain-containing protein

1

5

High-throughput

0.464

High

145087

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.464

High

145081

SPD2
Spindle-defective protein 2

1

0

Small-scale

0.460

High

145069

O01861
Very Early Transcript

1

1

Small-scale

0.439

High

113220

G5EFG1
PDZ and LIM domain protein Zasp

1

7

Small-scale

0.437

High

145099

LIN41
Protein lin-41

1

12

Small-scale

0.437

High

145090

Q22387
Centrosomal protein of 162 kDa

1

0

High-throughput

0.265

Low

145094

YRMC
Uncharacterized protein R06F6.12

1

0

High-throughput

0.265

Low

145097

Q9GYG1
C2H2-type domain-containing protein

1

0

High-throughput

0.265

Low

145098

Q9N4A9
NAD(+) kinase

1

0

High-throughput

0.265

Low

103974

F5GU62
Uncharacterized protein

1

0

Small-scale

0.251

Low

113750

HIF1
Hypoxia-inducible factor 1

1

0

Small-scale

0.251

Low

145085

LIN13
Zinc finger protein lin-13

1

0

Small-scale

0.251

Low

145086

Q19748
SUppressor of Pkc-3

1

0

Small-scale

0.251

Low

145096

Q9BKP3
SHOCT domain-containing protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025