Interactor 1: PTEN (O08586)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN
Interactor 2: NHRF2 (Q9JHL1)
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (Octs2) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)
Gene: Nherf2
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 0.60 | 0.578 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16456542 |
| Identification Methods | pull down, anti bait coimmunoprecipitation, chromatography technology |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043491 - phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051898 - negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Homologous interactions | 11 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
