HitPredict

Interactor 1: CI072 (Q96LT7)
Guanine nucleotide exchange factor C9orf72
Gene: C9orf72

Interactor 2: WDR41 (Q9HAD4)
WD repeat-containing protein 41
Gene: WDR41

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

The method score is based on:

Property	Details
Experiments	27617292, 27103069, 30669939, 33961781, 37317656, 29950492
Identification Methods	biochemical, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	association, physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005096 - GTPase activator activity GO:0005737 - cytoplasm GO:0006914 - autophagy GO:0010506 - regulation of autophagy GO:0032045 - guanyl-nucleotide exchange factor complex and 2 others more... GO:0045920 - negative regulation of exocytosis GO:0050777 - negative regulation of immune response
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	481
Hs

1	459

Service provided by Combinatics, Japan

Last updated: 11Aug2025