Interactor 1: LRRC7 (Q96NW7)
Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1)
Gene: LRRC7

Interactor 2: SHAN3 (Q9BYB0)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2)
Gene: SHANK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 39256359
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~PDZ_6, PDZ~SAM_1, PDZ~SH3_2
Common GO terms GO:0005829 - cytosol
GO:0014069 - postsynaptic density
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1537
Hs

1 1806
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025