Protein: SHAN1
SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP)

Gene: SHAN1, SHANK1
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q9Y566

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007616 - long-term memory
GO:0008306 - associative learning
GO:0014069 - postsynaptic density

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1462708

BAIP2
BAR/IMD domain-containing adapter protein 2

2

20

Small-scale

0.815

High

1417997

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

17

Small-scale

0.793

High

1491491

SHAN1
SH3 and multiple ankyrin repeat domains protein 1

2

16

Small-scale

0.793

High

1122000

ARHG7
Rho guanine nucleotide exchange factor 7

1

16

Small-scale

0.740

High

1117539

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

20

Small-scale

0.724

High

938149

ANM2
Protein arginine N-methyltransferase 2

1

2

High-throughput

0.698

High

1146499

KS6A2
Ribosomal protein S6 kinase alpha-2

1

4

High-throughput

0.692

High

909259

NEK4
Serine/threonine-protein kinase Nek4

1

15

High-throughput

0.691

High

980608

H4
Histone H4

1

1

High-throughput

0.665

High

838206

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

High-throughput

0.663

High

1460062

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

13

Small-scale

0.647

High

1399285

LRRC7
Leucine-rich repeat-containing protein 7

1

6

Small-scale

0.637

High

1418554

ACE2
Angiotensin-converting enzyme 2

2

3

Small-scale

0.629

High

1006128

DLG4
Disks large homolog 4

1

14

Small-scale

0.618

High

1141108

KIF14
Kinesin-like protein KIF14

1

13

High-throughput

0.618

High

154406

DLGP1
Disks large-associated protein 1

1

19

Small-scale

0.575

High

896945

DYN2
Dynamin-2

1

6

Small-scale

0.573

High

722889

SSR2
Somatostatin receptor type 2

1

6

Small-scale

0.561

High

1430012

SHRPN
Sharpin

1

4

Small-scale

0.552

High

239459

AGRB2
Adhesion G protein-coupled receptor B2

1

4

Small-scale

0.541

High

338667

AGRL2
Adhesion G protein-coupled receptor L2

1

5

Small-scale

0.541

High

900245

FXR1
RNA-binding protein FXR1

1

7

High-throughput

0.541

High

1365029

TSC1
Hamartin

1

20

High-throughput

0.541

High

987509

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

1

High-throughput

0.515

High

659649

CRCM
Colorectal mutant cancer protein

1

4

High-throughput

0.501

High

828267

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

8

Small-scale

0.501

High

862586

YAP1
Transcriptional coactivator YAP1

1

19

High-throughput

0.501

High

1032079

CAC1D
Voltage-dependent L-type calcium channel subunit alpha-1D

1

11

Small-scale

0.501

High

1308145

TB10C
Carabin

1

2

High-throughput

0.501

High

1429037

WWTR1
WW domain-containing transcription regulator protein 1

1

16

High-throughput

0.501

High

1135969

MELT
Ventricular zone-expressed PH domain-containing protein homolog 1

1

0

High-throughput

0.480

High

1294343

TM219
Insulin-like growth factor-binding protein 3 receptor

1

0

High-throughput

0.480

High

1417369

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.480

High

1028465

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

904424

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

1458979

KLOT
Klotho

1

0

Small-scale

0.458

High

1005281

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

1217460

GKAP1
G kinase-anchoring protein 1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025