HitPredict

Interactor 1: DIAP1 (O08808)
Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (p140mDIA) (mDIA1)
Gene: Diaph1

Interactor 2: DIAP1 (O08808)
Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (p140mDIA) (mDIA1)
Gene: Diaph1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 16472745, 12906795, 10559899
Identification Methods isothermal titration calorimetry, x-ray crystallography, chromatography technology, pull down, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Drf_FH3~Drf_FH3, Drf_FH3~Drf_GBD, Drf_FH3~FH2, Drf_GBD~Drf_GBD, FH2~FH2
Common GO terms GO:0003779 - actin binding
GO:0005522 - profilin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
and 26 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1255
Mm

1 1255
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024