HitPredict

Interactor 1: PIGS (Q96S52)
GPI-anchor transamidase component PIGS (Phosphatidylinositol-glycan biosynthesis class S protein)
Gene: PIGS

Interactor 2: PIGU (Q9H490)
GPI-anchor transamidase component PIGU (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U) (Phosphatidylinositol glycan anchor biosynthesis class U protein)
Gene: PIGU

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 26496610, 12802054
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PIG-S~PIG-U
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0016020 - membrane
GO:0016255 - attachment of GPI anchor to protein
GO:0042765 - GPI-anchor transamidase complex
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 555
Hs

1 435
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025