HitPredict

Interactor 1: E2F1 (O09139)
Transcription factor E2F1 (E2F-1)
Gene: E2F1

Interactor 2: RB (P33568)
Retinoblastoma-associated protein (pRb) (Rb) (pp105)
Gene: Rb1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 9697699
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E2F_CC-MB~Rb_C
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005667 - transcription regulator complex
and 10 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 432
Rn

1 920
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024